The centenary of insulin discovery represents an important opportunity to transform diabetes
from a fatal diagnosis into a medically manageable chronic condition. Insulin is a key …

Evidence is accumulating that the gut microbiome is involved in the aetiology of obesity and
obesity-related complications such as nonalcoholic fatty liver disease (NAFLD), insulin …

Metabolic syndrome is a cluster of metabolic risk factors, characterized by abdominal
obesity, dyslipidemia, low levels of high-density lipoprotein cholesterol (HDL-c) …

As years progress, we are found more often in a postprandial than a postabsorptive state.
Chrononutrition is an integral part of metabolism, pancreatic function, and hormone …

Evidence is increasing that disturbances in the gut microbiome may play a significant role in
the etiology of obesity and type 2 diabetes. The short chain fatty acid butyrate, a major end …

The connection between the gut microbiota and the aetiology of obesity and cardiometabolic
disorders is increasingly being recognized by clinicians. Our gut microbiota might affect the …

It is well known that an unhealthy lifestyle is a major risk factor for metabolic diseases, while
in recent years, accumulating evidence has demonstrated that the gut microbiome and its …

Inadequate or excessive nutrient consumption leads to oxidative stress, which may disrupt
oxidative homeostasis, activate a cascade of molecular pathways, and alter the metabolic …

Insulin resistance is a metabolic disorder affecting multiple tissues and is a precursor event
to type 2 diabetes (T2D). As T2D affects over 425 million people globally, there is an …

Short-chain fatty acids (SCFA), formed by microbial fermentation, are believed to be involved
in the aetiology of obesity and diabetes. This study investigated the effects of colonic …