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[HTML][HTML] Identification of new rofecoxib-based cyclooxygenase-2 inhibitors: A bioinformatics approach
RP Leão, JV Cruz, GV da Costa, JN Cruz… - Pharmaceuticals, 2020 - mdpi.com
The cyclooxygenase-2 receptor is a therapeutic target for planning potential drugs with anti-
inflammatory activity. The selective cyclooxygenase-2 (COX-2) inhibitor rofecoxib was …
inflammatory activity. The selective cyclooxygenase-2 (COX-2) inhibitor rofecoxib was …
Prodigiosin/PU-H71 as a novel potential combined therapy for triple negative breast cancer (TNBC): preclinical insights
Prodigiosin, a secondary metabolite red pigment produced by Serratia marcescens, has an
interesting apoptotic efficacy against cancer cell lines with low or no toxicity on normal cells …
interesting apoptotic efficacy against cancer cell lines with low or no toxicity on normal cells …
Highly potent natural fungicides identified in silico against the cereal killer fungus Magnaporthe oryzae
Magnaporthe oryzae is one of the most notorious fungal pathogens that causes blast
disease in cereals, and results in enormous loss of grain production. Many chemical …
disease in cereals, and results in enormous loss of grain production. Many chemical …
In-silico prediction of highly promising natural fungicides against the destructive blast fungus Magnaporthe oryzae
Magnaporthe oryzae causes destructive blast disease in more than 50 species of the major
cereal crops rice, wheat and maize and destroys food of millions of people worldwide …
cereal crops rice, wheat and maize and destroys food of millions of people worldwide …
Larvicidal activity of coumarin derivatives on Toxocara canis larvae, cytotoxicity analysis, and in silico bioavailability studies
DC Rodrigues, CN de Oliveira da Cunha… - Parasitology …, 2024 - Springer
Human toxocariasis is a neglected anthropozoonosis with global distribution. Treatment is
based on the administration of anthelmintics; however, their effectiveness at the tissue level …
based on the administration of anthelmintics; however, their effectiveness at the tissue level …
Evaluating chemotherapeutic potential of soya-isoflavonoids against high penetrance genes in triple-negative breast cancer
P Chatterjee, S Banerjee - Journal of Biomolecular Structure and …, 2024 - Taylor & Francis
Triple-negative breast cancer (TNBC) is the most aggressive molecular subtype of breast
cancer (BC) associated with a poor prognosis. Owing to the structural similarity with 17-β …
cancer (BC) associated with a poor prognosis. Owing to the structural similarity with 17-β …
In silico molecular docking evaluation reveals high potencies of some natural antifungal metabolites on melanin biosynthesis and appressoria formation enzymes in …
Magnaporthe oryzae is one of the most notorious fungal pathogens that causes blast
disease in cereals and results in enormous loss of grain production. Many chemical …
disease in cereals and results in enormous loss of grain production. Many chemical …
In Silico Screening of Triphala Churna against Bacterial Agents
LS Dhivya, M Haritha, GV Anjana… - Journal of Natural …, 2022 - informaticsjournals.co.in
Abstract Triphala Churna consisting Triphala and its constituents have been revealed to
have antibacterial properties against human pathogens. The phenolic ring of …
have antibacterial properties against human pathogens. The phenolic ring of …
[PDF][PDF] Computational Analysis of Pharmacokinetic, Bioactivity and Toxicity Parameters of Some Selected Oral-hypoglycaemic Agents Shashank Shekhar Mishra …
S Sharma, HP Singh - 2018 - chemrj.org
Diabetes mellitus is a chronic, lifelong condition that affects body's ability to use the energy
found in food. The number of patients with DM is markedly increasing worldwide. Globally …
found in food. The number of patients with DM is markedly increasing worldwide. Globally …
[PDF][PDF] In Silico Pharmacokinetic, Bioactivity and Toxicity Study of Some Selected Anti-Anginal Agents
SS Mishra, N Kumar, H Pandiya, HP Singh… - International Journal of … - scholar.archive.org
Angina pectoris is the major cardio-vascular disease that occurs due to the imbalance
between blood supply and demand that results obstruction of coronary arteries. WHO …
between blood supply and demand that results obstruction of coronary arteries. WHO …