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[HTML][HTML] Hyaluronic acid: a powerful biomolecule with wide-ranging applications—a comprehensive review
Hyaluronic acid (HA) is a glycosaminoglycan widely distributed in the human body,
especially in body fluids and the extracellular matrix of tissues. It plays a crucial role not only …
especially in body fluids and the extracellular matrix of tissues. It plays a crucial role not only …
Shattering barriers toward clinically meaningful MSC therapies
More than 1050 clinical trials are registered at FDA. gov that explore multipotent
mesenchymal stromal cells (MSCs) for nearly every clinical application imaginable …
mesenchymal stromal cells (MSCs) for nearly every clinical application imaginable …
Mesenchymal stromal cell homing: mechanisms and strategies for improvement
Mesenchymal stromal cells (MSCs) have been widely investigated for their therapeutic
potential in regenerative medicine, owing to their ability to home damaged tissue and serve …
potential in regenerative medicine, owing to their ability to home damaged tissue and serve …
Manufacturing of primed mesenchymal stromal cells for therapy
JQ Yin, J Zhu, JA Ankrum - Nature biomedical engineering, 2019 - nature.com
Mesenchymal stromal cells (MSCs) for basic research and clinical applications are
manufactured and developed as unique cell products by many different manufacturers and …
manufactured and developed as unique cell products by many different manufacturers and …
Biomimetic cell-derived nanocarriers in cancer research
Nanoparticles have now long demonstrated capabilities that make them attractive to use in
biology and medicine. Some of them, such as lipid nanoparticles (SARS-CoV-2 vaccines) or …
biology and medicine. Some of them, such as lipid nanoparticles (SARS-CoV-2 vaccines) or …
Concise review: mesenchymal stem cell-based drug delivery: the good, the bad, the ugly, and the promise
TEG Krueger, DLJ Thorek… - Stem cells …, 2018 - academic.oup.com
The development of mesenchymal stem cells (MSCs) as cell-based drug delivery vectors for
numerous clinical indications, including cancer, has significant promise. However, a …
numerous clinical indications, including cancer, has significant promise. However, a …
Genetically engineered and enucleated human mesenchymal stromal cells for the targeted delivery of therapeutics to diseased tissue
H Wang, CN Alarcón, B Liu, F Watson… - Nature biomedical …, 2022 - nature.com
Targeting the delivery of therapeutics specifically to diseased tissue enhances their efficacy
and decreases their side effects. Here we show that mesenchymal stromal cells with their …
and decreases their side effects. Here we show that mesenchymal stromal cells with their …
Biomolecules-derived biomaterials
Human civilization has witnessed the use of materials-derived from biomolecules of plants
and animal origin for biomedical applications since ancient era. In recent years, precision …
and animal origin for biomedical applications since ancient era. In recent years, precision …
Mesenchymal stem cell exosomes as a cell-free therapy for nerve injury–induced pain in rats
SJ Shiue, RH Rau, HS Shiue, YW Hung, ZX Li… - Pain, 2019 - journals.lww.com
Nerve injury–induced neuropathic pain is difficult to treat. In this study, we used exosomes
derived from human umbilical cord mesenchymal stem cell (UCMSC) as a cell-free therapy …
derived from human umbilical cord mesenchymal stem cell (UCMSC) as a cell-free therapy …
Advancements in 3D cell culture systems for personalizing anti-cancer therapies
Over 90% of potential anti-cancer drug candidates results in translational failures in clinical
trials. The main reason for this failure can be attributed to the non-accurate pre-clinical …
trials. The main reason for this failure can be attributed to the non-accurate pre-clinical …