Inorganic nanomaterials with rapid clearance for biomedical applications
Inorganic nanomaterials that have inherently exceptional physicochemical properties (eg,
catalytic, optical, thermal, electrical, or magnetic performance) that can provide desirable …
catalytic, optical, thermal, electrical, or magnetic performance) that can provide desirable …
Glucose oxidase‐instructed multimodal synergistic cancer therapy
Over the past 3 years, glucose oxidase (GOx) has aroused great research interest in the
context of cancer treatment due to its inherent biocompatibility and biodegradability, and its …
context of cancer treatment due to its inherent biocompatibility and biodegradability, and its …
Nanocatalytic theranostics with glutathione depletion and enhanced reactive oxygen species generation for efficient cancer therapy
Chemodynamic therapy (CDT) is an emerging therapy method that kills cancer cells by
converting intracellular hydrogen peroxide (H2O2) into highly toxic hydroxyl radicals (• OH) …
converting intracellular hydrogen peroxide (H2O2) into highly toxic hydroxyl radicals (• OH) …
Multifunctional metal-organic framework-based nanoreactor for starvation/oxidation improved indoleamine 2, 3-dioxygenase-blockade tumor immunotherapy
L Dai, M Yao, Z Fu, X Li, X Zheng, S Meng… - Nature …, 2022 - nature.com
Inhibited immune response and low levels of delivery restrict starvation cancer therapy
efficacy. Here, we report on the co-delivery of glucose oxidase (GOx) and indoleamine 2, 3 …
efficacy. Here, we report on the co-delivery of glucose oxidase (GOx) and indoleamine 2, 3 …
Biodegradable manganese-doped calcium phosphate nanotheranostics for traceable cascade reaction-enhanced anti-tumor therapy
Glucose oxidase (GOx) has been recognized as a “star” enzyme catalyst involved in cancer
treatment in the past few years. Herein, GOx is mineralized with manganese-doped calcium …
treatment in the past few years. Herein, GOx is mineralized with manganese-doped calcium …
Calcium-overload-mediated tumor therapy by calcium peroxide nanoparticles
Calcium overload, characterized by an abnormal cytoplasm accumulation of free calcium
ions (Ca 2+), is a widely recognized cause of damage in numerous cell types and even of …
ions (Ca 2+), is a widely recognized cause of damage in numerous cell types and even of …
Lactate‐Oxidase‐Instructed Cancer Diagnosis and Therapy
Lactate oxidase (LOx) has attracted extensive interest in cancer diagnosis and therapy in
recent years owing to its specific catalysis on l‐lactate; its catalytic process consumes …
recent years owing to its specific catalysis on l‐lactate; its catalytic process consumes …
Enzyme‐mediated tumor starvation and phototherapy enhance mild‐temperature photothermal therapy
Compared with conventional tumor photothermal therapy (PTT), mild‐temperature PTT
brings less damage to normal tissues, but also tumor thermoresistance, introduced by the …
brings less damage to normal tissues, but also tumor thermoresistance, introduced by the …
Enzyme mimics for engineered biomimetic cascade nanoreactors: mechanism, applications, and prospects
Multiple enzyme‐driven biological catalytic cascades occur in living organisms, guiding
highly efficient and selective transformations of substrates. Inspired by the merits of these …
highly efficient and selective transformations of substrates. Inspired by the merits of these …
Recent advances in glucose‐oxidase‐based nanocomposites for tumor therapy
M Wang, D Wang, Q Chen, C Li, Z Li, J Lin - Small, 2019 - Wiley Online Library
Glucose oxidase (GOx) can react with intracellular glucose and oxygen (O2) to produce
hydrogen peroxide (H2O2) and gluconic acid, which can cut off the nutrition source of …
hydrogen peroxide (H2O2) and gluconic acid, which can cut off the nutrition source of …