The evolving nexus of sleep and depression

DT Plante - American Journal of Psychiatry, 2021 - Am Psychiatric Assoc
Sleep disturbances and depression are closely linked and share a bidirectional relationship.
These interconnections can inform the pathophysiology underlying each condition. Insomnia …

[HTML][HTML] A narrative review on insomnia and hypersomnolence within Major Depressive Disorder and bipolar disorder: A proposal for a novel psychometric protocol

CS Guerrera, FM Boccaccio, S Varrasi… - Neuroscience & …, 2024 - Elsevier
Sleep disorders have become increasingly prevalent, with many adults worldwide reporting
sleep dissatisfaction. Major Depressive Disorder (MDD) and Bipolar Disorder (BD) are …

Inflammation, tau pathology, and synaptic integrity associated with sleep spindles and memory prior to β-amyloid positivity

BA Mander, A Dave, KK Lui, KE Sprecher, D Berisha… - Sleep, 2022 - academic.oup.com
Abstract Study Objectives Fast frequency sleep spindles are reduced in aging and
Alzheimer's disease (AD), but the mechanisms and functional relevance of these deficits …

Trajectories of sleep duration and timing before dementia: a 14-year follow-up study

C Cavaillès, I Carrière, M Wagner, JF Dartigues… - Age and …, 2022 - academic.oup.com
Background given the complex relationship between sleep and neurodegenerative
processes, it is important to examine whether changes in sleep patterns occur prior or close …

How is psychological stress linked to sleep quality? The mediating role of functional connectivity between the sensory/somatomotor network and the cingulo-opercular …

L Zhang, D Li, H Yin - Brain and Cognition, 2020 - Elsevier
How the functional connectivity of brain networks affects the relationship between
psychological stress and sleep quality remains unclear. To better understand the …

Characteristics associated with hypersomnia and excessive daytime sleepiness identified by extended polysomnography recording

E Evangelista, AL Rassu, L Barateau, R Lopez… - Sleep, 2021 - academic.oup.com
Abstract Study Objectives Hypersomnolence, defined by excessive daytime sleepiness
(EDS) or excessive quantity of sleep (EQS), has been associated with increased morbidity …

Sleep alterations in major depressive disorder and insomnia disorder: a network meta-analysis of polysomnographic studies

C Leitner, F Dalle Piagge, T Tomic, F Nozza… - Sleep Medicine …, 2025 - Elsevier
Major depressive disorder (MDD) and Insomnia disorder (ID) are characterized by sleep
alterations. To define their polysomnographic profiles, we conducted a Network Meta …

The left temporal transverse cortex is affected by poor sleep quality, which in turn contributes to depressive symptoms in older adults

W Li, L Sun, L Yue, S **ao - Heliyon, 2023 - cell.com
Sleep quality is critical for improving mental health among older adults. Despite this, there is
a dearth of studies examining the correlation between sleep quality and emotional …

Hypersomnolence is associated with non-remission of major depressive disorder

MMS Cheung, SP Lam, SWH Chau, NY Chan, TMH Li… - Sleep Medicine, 2024 - Elsevier
Objective This study aimed to investigate the prevalence, clinical correlates and the
relationship between hypersomnolence and clinical outcomes in a cohort of MDD patients …

[HTML][HTML] Pathophysiological models of hypersomnolence associated with depression

C Moderie, DB Boivin - Biological Psychiatry Global Open Science, 2024 - Elsevier
Up to a quarter of patients with depression experience hypersomnolence (eg., excessive
daytime sleepiness, hypersomnia and/or sleep inertia), which is associated with treatment …