Xenobiotic metabolism and transport in Caenorhabditis elegans
Caenorhabditis elegans has emerged as a major model in biomedical and environmental
toxicology. Numerous papers on toxicology and pharmacology in C. elegans have been …
toxicology. Numerous papers on toxicology and pharmacology in C. elegans have been …
Polymeric zinc-doped nanoparticles for high performance in restorative dentistry
M Toledano, M Vallecillo-Rivas, FS Aguilera… - Journal of dentistry, 2021 - Elsevier
Objectives The aim was to state the different applications and the effectiveness of polymeric
zinc-doped nanoparticles to achieve dentin remineralization. Data, sources and study …
zinc-doped nanoparticles to achieve dentin remineralization. Data, sources and study …
[HTML][HTML] Juggling cadmium detoxification and zinc homeostasis: a division of labour between the two C. elegans metallothioneins
YJ Essig, OI Leszczyszyn, N Almutairi… - Chemosphere, 2024 - Elsevier
The chemical properties of toxic cadmium and essential zinc are very similar, and organisms
require intricate mechanisms that drive selective handling of metals. Previously regarded as …
require intricate mechanisms that drive selective handling of metals. Previously regarded as …
Cadmium hijacks the high zinc response by binding and activating the HIZR-1 nuclear receptor
Cadmium is an environmental pollutant and significant health hazard that is similar to the
physiological metal zinc. In Caenorhabditis elegans, high zinc homeostasis is regulated by …
physiological metal zinc. In Caenorhabditis elegans, high zinc homeostasis is regulated by …
Cadmium stress dictates central carbon flux and alters membrane composition in Streptococcus pneumoniae
Metal ion homeostasis is essential for all forms of life. However, the breadth of intracellular
impacts that arise upon dysregulation of metal ion homeostasis remain to be elucidated …
impacts that arise upon dysregulation of metal ion homeostasis remain to be elucidated …
The molecular basis of Acinetobacter baumannii cadmium toxicity and resistance
Acinetobacter species are ubiquitous Gram-negative bacteria that can be found in water, in
soil, and as commensals of the human skin. The successful inhabitation of Acinetobacter …
soil, and as commensals of the human skin. The successful inhabitation of Acinetobacter …
Natural variation in the sequestosome-related gene, sqst-5, underlies zinc homeostasis in Caenorhabditis elegans
Zinc is an essential trace element that acts as a co-factor for many enzymes and
transcription factors required for cellular growth and development. Altering intracellular zinc …
transcription factors required for cellular growth and development. Altering intracellular zinc …
Toxicity of Per-and Polyfluoroalkyl Substances to Nematodes
T Ma, X Pan, T Wang, X Li, Y Luo - Toxics, 2023 - mdpi.com
Per-and polyfluoroalkyl substances (PFASs) are a class of compounds that persist in the
environment globally. Besides being transported to the soil and sediments, which act as …
environment globally. Besides being transported to the soil and sediments, which act as …
The effect of metal mixture composition on toxicity to C. elegans at individual and population levels
The toxicity of zinc (Zn), copper (Cu), and cadmium (Cd) to the nematode Caenorhabditis
elegans was characterised under single metal and mixture scenarios at different …
elegans was characterised under single metal and mixture scenarios at different …
A conserved CCM complex promotes apoptosis non-autonomously by regulating zinc homeostasis
EM Chapman, B Lant, Y Ohashi, B Yu… - Nature …, 2019 - nature.com
Apoptotic death of cells damaged by genotoxic stress requires regulatory input from
surrounding tissues. The C. elegans scaffold protein KRI-1, ortholog of mammalian …
surrounding tissues. The C. elegans scaffold protein KRI-1, ortholog of mammalian …