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miRNAs as biomarkers in disease: latest findings regarding their role in diagnosis and prognosis
CE Condrat, DC Thompson, MG Barbu, OL Bugnar… - Cells, 2020 - mdpi.com
MicroRNAs (miRNAs) represent a class of small, non-coding RNAs with the main roles of
regulating mRNA through its degradation and adjusting protein levels. In recent years …
regulating mRNA through its degradation and adjusting protein levels. In recent years …
Current and future biomarkers in multiple sclerosis
J Yang, M Hamade, Q Wu, Q Wang, R Axtell… - International journal of …, 2022 - mdpi.com
Multiple sclerosis (MS) is a debilitating autoimmune disorder. Currently, there is a lack of
effective treatment for the progressive form of MS, partly due to insensitive readout for …
effective treatment for the progressive form of MS, partly due to insensitive readout for …
MicroRNA-146a: a dominant, negative regulator of the innate immune response
MicroRNAs (miRNAs) are a class of small non-coding RNA molecules that can play critical
roles as regulators of numerous pathways and biological processes including the immune …
roles as regulators of numerous pathways and biological processes including the immune …
[HTML][HTML] MicroRNA alteration, application as biomarkers, and therapeutic approaches in neurodegenerative diseases
MicroRNAs (miRNAs) are essential post-transcriptional gene regulators involved in various
neuronal and non-neuronal cell functions and play a key role in pathological conditions …
neuronal and non-neuronal cell functions and play a key role in pathological conditions …
miR-22 gene therapy treats HCC by promoting anti-tumor immunity and enhancing metabolism
MicroRNA-22 (miR-22) can be induced by beneficial metabolites that have metabolic and
immune effects, including retinoic acids, bile acids, vitamin D 3, and short-chain fatty acids …
immune effects, including retinoic acids, bile acids, vitamin D 3, and short-chain fatty acids …
MicroRNA-21 is a versatile regulator and potential treatment target in central nervous system disorders
X Bai, Z Bian - Frontiers in molecular neuroscience, 2022 - frontiersin.org
MicroRNAs (miRNAs) are a class of endogenous, non-coding, single-stranded RNAs with a
length of approximately 22 nucleotides that are found in eukaryotes. miRNAs are involved in …
length of approximately 22 nucleotides that are found in eukaryotes. miRNAs are involved in …
Plasma miR-34a-5p and miR-545-3p as early biomarkers of Alzheimer's disease: potential and limitations
Plasma microRNAs (miRNAs) have been proposed as potential biomarkers in Alzheimer's
disease (AD). Here, we explored their use as early sensors of the preclinical phase of the …
disease (AD). Here, we explored their use as early sensors of the preclinical phase of the …
[HTML][HTML] microRNA diagnostic panel for Alzheimer's disease and epigenetic trade-off between neurodegeneration and cancer
S Nagaraj, KM Zoltowska, K Laskowska-Kaszub… - Ageing research …, 2019 - Elsevier
Abstract microRNAs (miRNAs) have been extensively studied as potential biomarkers for
Alzheimer's disease (AD). Their profiles have been analyzed in blood, cerebrospinal fluid …
Alzheimer's disease (AD). Their profiles have been analyzed in blood, cerebrospinal fluid …
Impaired oligodendrocyte maturation in preterm infants: Potential therapeutic targets
E Van Tilborg, CJ Heijnen, MJ Benders, F van Bel… - Progress in …, 2016 - Elsevier
Preterm birth is an evolving challenge in neonatal health care. Despite declining mortality
rates among extremely premature neonates, morbidity rates remain very high. Currently …
rates among extremely premature neonates, morbidity rates remain very high. Currently …
The role of miRNAs in multiple sclerosis pathogenesis, diagnosis, and therapeutic resistance
In recent years, microRNAs (miRNAs) have gained increased attention from researchers
around the globe. Although it is twenty nucleotides long, it can modulate several gene …
around the globe. Although it is twenty nucleotides long, it can modulate several gene …