Boceprevir, GC-376, and calpain inhibitors II, XII inhibit SARS-CoV-2 viral replication by targeting the viral main protease
A new coronavirus SARS-CoV-2, also called novel coronavirus 2019 (2019-nCoV), started
to circulate among humans around December 2019, and it is now widespread as a global …
to circulate among humans around December 2019, and it is now widespread as a global …
Dopamine reduction in the substantia nigra of Parkinson's disease patients confirmed by in vivo magnetic resonance spectroscopic imaging
A Gröger, R Kolb, R Schäfer, U Klose - PloS one, 2014 - journals.plos.org
Objectives Metabolic changes in the substantia nigra of patients with Parkinson's disease
were previously investigated in different molecular-pathological examinations. The aim of …
were previously investigated in different molecular-pathological examinations. The aim of …
Thalamic involvement in fluctuating cognition in dementia with Lewy bodies: magnetic resonance evidences
Dementia with Lewy bodies (DLB) is characterized by fluctuation in cognition and attention.
Thalamocortical connectivity and integrity of thalami are central to attentional function. We …
Thalamocortical connectivity and integrity of thalami are central to attentional function. We …
Preclinical magnetic resonance imaging and spectroscopy studies of memory, aging, and cognitive decline
M Febo, TC Foster - Frontiers in aging neuroscience, 2016 - frontiersin.org
Neuroimaging provides for non-invasive evaluation of brain structure and activity and has
been employed to suggest possible mechanisms for cognitive aging in humans. However …
been employed to suggest possible mechanisms for cognitive aging in humans. However …
GABA content within the ventromedial prefrontal cortex is related to trait anxiety
The ventromedial prefrontal cortex (vmPFC) plays a key role in emotion processing and
regulation. vmPFC dysfunction may lead to disinhibition of amygdala causing high anxiety …
regulation. vmPFC dysfunction may lead to disinhibition of amygdala causing high anxiety …
Modeling nigrostriatal degeneration in organotypic cultures, a new ex vivo model of Parkinson's disease
Parkinson's disease (PD) is the second most frequent neurodegenerative disorder afflicting
2% of the population older than 65 years worldwide. Recently, brain organotypic slices have …
2% of the population older than 65 years worldwide. Recently, brain organotypic slices have …
High γ‐aminobutyric acid content within the medial prefrontal cortex is a functional signature of somatic symptoms disorder in patients with Parkinson's disease
S Delli Pizzi, R Franciotti, A Ferretti… - Movement …, 2020 - Wiley Online Library
Background The dysfunctional activity of the medial prefrontal cortex has been associated
with the appearance of the somatic symptom disorder, a key feature of the Parkinson's …
with the appearance of the somatic symptom disorder, a key feature of the Parkinson's …
Detecting dopaminergic neuronal degeneration using diffusion tensor imaging in a rotenone-induced rat model of Parkinson's disease: fractional anisotropy and mean …
L Liu, D Du, T Zheng, Y Fang, Y Chen… - Neural regeneration …, 2017 - journals.lww.com
Dopamine content in the basal ganglia is strongly associated with the degree of
dopaminergic neuron loss in the substantia nigra pars compacta. Symptoms of Parkinson's …
dopaminergic neuron loss in the substantia nigra pars compacta. Symptoms of Parkinson's …
Metabolic disturbances in the striatum and substantia nigra in the onset and progression of MPTP-induced Parkinsonism model
Y Lu, X Zhang, L Zhao, C Yang, L Pan, C Li… - Frontiers in …, 2018 - frontiersin.org
Metabolic confusion has been linked to the pathogenesis of Parkinson's disease (PD), while
the dynamic changes associated with the onset and progression of PD remain unclear …
the dynamic changes associated with the onset and progression of PD remain unclear …
Safety and effects on motor cortex excitability of five cathodal transcranial direct current stimulation sessions in 25 hours
Objective To assess the safety and effects on motor cortex excitability of five cathodal-tDCS
sessions (charge density 342.9 C/m 2) delivered over the dominant motor cortex with a …
sessions (charge density 342.9 C/m 2) delivered over the dominant motor cortex with a …