A crosstalk between TGF-β/Smad3 and Wnt/β-catenin pathways promotes vascular smooth muscle cell proliferation
DM DiRenzo, MA Chaudhary, X Shi, SR Franco, J Zent… - Cellular signalling, 2016 - Elsevier
Rationale Endovascular interventions performed for atherosclerotic lesions trigger excessive
vascular smooth muscle cell (SMC) proliferation leading to intimal hyperplasia. Our previous …
vascular smooth muscle cell (SMC) proliferation leading to intimal hyperplasia. Our previous …
Dynamic changes in chromatin accessibility are associated with the atherogenic transitioning of vascular smooth muscle cells
Aims De-differentiation and activation of pro-inflammatory pathways are key transitions
vascular smooth muscle cells (SMCs) make during atherogenesis. Here, we explored the …
vascular smooth muscle cells (SMCs) make during atherogenesis. Here, we explored the …
CHD8 dosage regulates transcription in pluripotency and early murine neural differentiation
The chromatin remodeler CHD8 is among the most frequently mutated genes in autism
spectrum disorder (ASD). CHD8 has a dosage-sensitive role in ASD, but when and how it …
spectrum disorder (ASD). CHD8 has a dosage-sensitive role in ASD, but when and how it …
Chemokine mediated signalling within arteries promotes vascular smooth muscle cell recruitment
The preferential accumulation of vascular smooth muscle cells (vSMCs) on arteries versus
veins during early development is a well-described phenomenon, but the molecular …
veins during early development is a well-described phenomenon, but the molecular …
[HTML][HTML] Phenotypic characterization of adenomyosis occurring at the inner and outer myometrium
Y Kishi, K Shimada, T Fujii, T Uchiyama, C Yoshimoto… - PloS one, 2017 - journals.plos.org
Objective To estimate the phenotypic characterization of fibrotic process in adenomyosis
occurring at the inner or the outer myometrium. Methods Eight cases of adenomyosis …
occurring at the inner or the outer myometrium. Methods Eight cases of adenomyosis …
Dedifferentiation of vascular smooth muscle cells upon vessel injury
C Zhao, J Shen, Y Lu, H Ni, M **ang, Y **e - International …, 2025 - Elsevier
Highly differentiated mature vascular smooth muscle cells (VSMCs) are the predominant
type of cells constituting arterial walls, which are essential for maintaining the structural and …
type of cells constituting arterial walls, which are essential for maintaining the structural and …
The relationships between polymorphisms in genes encoding the growth factors TGF-β1, PDGFB, EGF, bFGF and VEGF-A and the restenosis process in patients with …
Background Neointima forming after stent implantation consists of vascular smooth muscle
cells (VSMCs) in 90%. Growth factors TGF-β1, PDGFB, EGF, bFGF and VEGF-A play an …
cells (VSMCs) in 90%. Growth factors TGF-β1, PDGFB, EGF, bFGF and VEGF-A play an …
CXCR3-CXCL11 Signaling Restricts Angiogenesis and Promotes Pericyte Recruitment
J Lee, ME Goeckel, A Levitas, S Colijn… - … , and vascular biology, 2024 - ahajournals.org
BACKGROUND: Endothelial cell (EC)–pericyte interactions are known to remodel in
response to hemodynamic forces; yet there is a lack of mechanistic understanding of the …
response to hemodynamic forces; yet there is a lack of mechanistic understanding of the …
LncRNA APOA1-AS facilitates proliferation and migration and represses apoptosis of VSMCs through TAF15-mediated SMAD3 mRNA stabilization
J Wang, Y Cai, H Lu, F Zhang, J Zheng - Cell Cycle, 2021 - Taylor & Francis
Coronary atherosclerosis (CAS) is a major cause of cardiovascular disease. Long non-
coding RNAs (lncRNAs) have been implicated as novel biomarkers in coronary artery …
coding RNAs (lncRNAs) have been implicated as novel biomarkers in coronary artery …
Cell sheet mechanics: How geometrical constraints induce the detachment of cell sheets from concave surfaces
Despite of the progress made to engineer structured microtissues such as BioMEMS and 3D
bioprinting, little control exists how microtissues transform as they mature, as the misbalance …
bioprinting, little control exists how microtissues transform as they mature, as the misbalance …