The human brain constitutes 2% of the body's total mass but uses 20% of the oxygen. The
rate of the brain's oxygen utilization can be derived from a knowledge of cerebral blood flow …

This article provides an overview of MRI methods exploiting magnetic susceptibility
properties of blood to assess cerebral oxygen metabolism, including the tissue oxygen …

Objective The objective of this study was to evaluate the whole-brain pattern of oxygen
extraction fraction (OEF), cerebral blood flow (CBF), and cerebral metabolic rate of oxygen …

Objectives Iron deposition and mitochondrial dysfunction are closely associated with the
genesis and progression of Parkinson's disease (PD). This study aims to extract …

We aimed to demonstrate the feasibility of whole brain oxygen extraction fraction (OEF)
map** for measuring lesion specific and regional OEF abnormalities in multiple sclerosis …

Purpose To improve accuracy and speed of quantitative susceptibility map** plus
quantitative blood oxygen level‐dependent magnitude (QSM+ qBOLD or QQ)‐based …

Objective Normal pressure hydrocephalus (NPH) is a neurodegenerative disease that is
potentially reversible by shunt surgery in approximately 60% of patients. Imaging may …

Purpose There are many approaches to the quantitative BOLD (qBOLD) technique
described in the literature, differing in pulse sequences, MRI parameters and data …

Abstract Background and Purpose We investigated the effects of aging, white matter
hyperintensities (WMH), and cognitive impairment on brain iron levels and cerebral oxygen …

Quantification of brain oxygenation and metabolism, both of which are indicators of the level
of brain activity, plays a vital role in understanding the cerebral perfusion and the …