Physical cues like morphology, light, electric signal, mechanic signal, magnetic signal, and
heat can be used as alternative regulators for expensive but short‐acting growth factors in …

Abstract Hydroxyapatite (HAp), a well-known biomaterial, has witnessed a remarkable
evolution over the years, transforming from a simple biocompatible substance to an …

After an osteosarcoma excision, recurrence, large bone defects, and soft tissue injury are
significant challenges for clinicians. Conventional treatment by implanting bone replacement …

Calcium phosphates (CaPs) are ubiquitous in nature and vertebrate bones and teeth, and
have high biocompatibility and promising applications in various biomedical fields …

One of the major issues in tissue engineering is regulation of stem cell differentiation toward
specific lineages. Unlike biological and chemical signals, physical signals with adjustable …

The coupled process of osteogenesis-angiogenesis plays a crucial role in periodontal tissue
regeneration. Although various cytokines or chemokines have been widely applied in …

Numerous studies have determined that physical cues, especially the nanotopography of
materials, play key roles in directing stem cell differentiation. However, most research on …

Nanomaterials are commonly considered as those materials in which the shape and
molecular composition at a nanometer scale can be controlled. Subsequently, they present …

Controllable osteoinduction maintained in the original defect area is the key to precise bone
repair. To meet the requirement of precise bone regeneration, a hydroxyapatite (HAp) …

Neural stem cells (NSCs) are thought to be the best seed cells for neurodegenerative
diseases therapy due to their potential to differentiate into either neurons or glial cells …