Silver nanoparticles for the therapy of tuberculosis

AF Tăbăran, CT Matea, T Mocan… - International journal …, 2020 - Taylor & Francis
Rapid emergence of aggressive, multidrug-resistant Mycobacteria strain represents the
main cause of the current antimycobacterial-drug crisis and status of tuberculosis (TB) as a …

Peptidoglycan NlpC/P60 peptidases in bacterial physiology and host interactions

ME Griffin, S Klupt, J Espinosa, HC Hang - Cell chemical biology, 2023 - cell.com
The bacterial cell wall is composed of a highly crosslinked matrix of glycopeptide polymers
known as peptidoglycan that dictates bacterial cell morphology and protects against …

Convolutional neural network-based annotation of bacterial type IV secretion system effectors with enhanced accuracy and reduced false discovery

J Hong, Y Luo, M Mou, J Fu, Y Zhang… - Briefings in …, 2020 - academic.oup.com
The type IV bacterial secretion system (SS) is reported to be one of the most ubiquitous SSs
in nature and can induce serious conditions by secreting type IV SS effectors (T4SEs) into …

Mycobacterium tuberculosis RipA Dampens TLR4-Mediated Host Protective Response Using a Multi-Pronged Approach Involving Autophagy, Apoptosis, Metabolic …

M Shariq, N Quadir, N Sharma, J Singh… - Frontiers in …, 2021 - frontiersin.org
Reductive evolution has endowed Mycobacterium tuberculosis (M. tb) with moonlighting in
protein functions. We demonstrate that RipA (Rv1477), a peptidoglycan hydrolase, activates …

Protein-protein interactions and their role in various diseases and their prediction techniques

G Rabbani, MH Baig, K Ahmad… - Current Protein and …, 2018 - ingentaconnect.com
Protein-protein interaction (PPI) is necessary for most of the biological processes and
requisite for host-pathogen communication. Most of the threatening human diseases are …

Mycobacterium tuberculosis protein MoxR1 enhances virulence by inhibiting host cell death pathways and disrupting cellular bioenergetics

N Quadir, M Shariq, JA Sheikh, J Singh, N Sharma… - Virulence, 2023 - Taylor & Francis
Mycobacterium tuberculosis (M. tb) utilizes the multifunctionality of its protein factors to
deceive the host. The unabated global incidence and prevalence of tuberculosis (TB) and …

Role of Bacterioferritin & Ferritin in M. tuberculosis Pathogenesis and Drug Resistance: A Future Perspective by Interactomic Approach

D Sharma, D Bisht - Frontiers in cellular and infection microbiology, 2017 - frontiersin.org
Tuberculosis is caused by Mycobacterium tuberculosis, one of the most successful and
deadliest human pathogen. Aminoglycosides resistance leads to emergence of extremely …

Role of iron in bacterial pathogenesis

SM Zughaier, P Cornelis - Frontiers in cellular and infection …, 2018 - frontiersin.org
Iron is the fourth-most abundant element on the earth, and it is needed by most organisms,
including bacteria. It exists in two oxidation states, Fe2+ and Fe3+, and is involved in many …

[HTML][HTML] The cytotoxic mycobacteriophage protein Phaedrus gp82 interacts with and modulates the activity of the host ATPase, MoxR

SA Binsabaan, KG Freeman, GF Hatfull… - Journal of Molecular …, 2023 - Elsevier
Approximately 70% of bacteriophage-encoded proteins are of unknown function. Elucidating
these protein functions represents opportunities to discover new phage-host interactions …

[LIVRE][B] Virulence factors and pathogenicity of Mycobacterium

G Echeverria-Valencia, S Flores-Villalva, CI Espitia - 2018 - books.google.com
Virulence, is referred as the ability of a pathogen to cause disease, and for mycobacteria it
depends on their ability to reside within host cells and evade the microbicidal mechanisms …