[HTML][HTML] Artificial Intelligence-Based Digital Biomarkers for Type 2 Diabetes: A Review

M Jabara, O Kose, G Perlman, S Corcos… - Canadian Journal of …, 2024 - Elsevier
Type 2 diabetes mellitus (T2DM), a complex metabolic disorder that burdens the healthcare
system, requires early detection and treatment. Recent strides in digital health technologies …

[HTML][HTML] Clinical validation of novel digital measures: statistical methods for reliability evaluation

B Ratitch, A Trigg, M Majumder, V Vlajnic… - Digital …, 2023 - karger.com
Background: Assessment of reliability is one of the key components of the validation process
designed to demonstrate that a novel clinical measure assessed by a digital health …

[HTML][HTML] Reverse engineering of digital measures: inviting patients to the conversation

I Clay, N Peerenboom, DE Connors, S Bourke… - Digital …, 2023 - karger.com
Background: Digital measures offer an unparalleled opportunity to create a more holistic
picture of how people who are patients behave in their real-world environments, thereby …

Interpretation of change in novel digital measures: a statistical review and tutorial

A Trigg, B Ratitch, F Kruesmann, M Majumder… - Digital …, 2025 - karger.com
Background Novel clinical measures assessed by a digital health technology tool require
thresholds to interpret change over time, such as the minimal clinically important difference …

Analysis Method of Real-World Digital Biomarkers for Clinical Impact in Cancer Patients

I Oakley-Girvan, Y Zhai, R Yunis, R Liu, SW Davis… - Digital …, 2025 - karger.com
Introduction: Wearable technologies can enhance measurements completed from home by
participants in decentralized clinical trials. These measurements have shown promise in …

[PDF][PDF] Clinical Validation of Novel Digital Measures: Statistical Methods for Reliability Evaluation

BRATM Majumderc, V Vlajnicc, NRR Nkulikiyinkae - 2023 - core.ac.uk
Background: Assessment of reliability is one of the key components of the validation process
designed to demonstrate that a novel clinical measure assessed by a digital health …

Progress Report: Pharma Adoption of Data Analytics

C Bahls - Applied Clinical Trials, 2023 - search.proquest.com
Abstract According to the 20-80 breakdown, a little math shows that if 720,000 data points
are analyzed and 2.8 million remain warehoused, a lot of data is left on the cutting room …