TGF-β Regulation of T Cells
WJ Chen - Annual review of immunology, 2023 - annualreviews.org
Transforming growth factor β (TGF-β) is a key cytokine regulating the development,
activation, proliferation, differentiation, and death of T cells. In CD4+ T cells, TGF-β maintains …
activation, proliferation, differentiation, and death of T cells. In CD4+ T cells, TGF-β maintains …
The precursors of CD8+ tissue resident memory T cells: from lymphoid organs to infected tissues
CD8+ tissue resident memory T cells (TRM cells) are essential for immune defence against
pathogens and malignancies, and the molecular processes that lead to TRM cell formation …
pathogens and malignancies, and the molecular processes that lead to TRM cell formation …
Discrete tissue microenvironments instruct diversity in resident memory T cell function and plasticity
Tissue-resident memory T (TRM) cells are non-recirculating cells that exist throughout the
body. Although TRM cells in various organs rely on common transcriptional networks to …
body. Although TRM cells in various organs rely on common transcriptional networks to …
[HTML][HTML] Chemokines and chemokine receptors during COVID-19 infection
Chemokines are crucial inflammatory mediators needed during an immune response to
clear pathogens. However, their excessive release is the main cause of hyperinflammation …
clear pathogens. However, their excessive release is the main cause of hyperinflammation …
[HTML][HTML] Intratumoral CD8+ T cells with a tissue-resident memory phenotype mediate local immunity and immune checkpoint responses in breast cancer
B Virassamy, F Caramia, P Savas, S Sant, J Wang… - Cancer Cell, 2023 - cell.com
CD8+ tumor-infiltrating lymphocytes with a tissue-resident memory T (T RM) cell phenotype
are associated with favorable prognosis in patients with triple-negative breast cancer …
are associated with favorable prognosis in patients with triple-negative breast cancer …
Runx3 programs CD8+ T cell residency in non-lymphoid tissues and tumours
Tissue-resident memory CD8+ T (TRM) cells are found at common sites of pathogen
exposure, where they elicit rapid and robust protective immune responses,. However, the …
exposure, where they elicit rapid and robust protective immune responses,. However, the …
Understanding subset diversity in T cell memory
Considerable advances have been made in recent years in understanding the generation
and function of memory T cells. Memory T cells are typically parsed into discreet subsets …
and function of memory T cells. Memory T cells are typically parsed into discreet subsets …
Tissue-resident CD4+ T helper cells assist the development of protective respiratory B and CD8+ T cell memory responses
Much remains unknown about the roles of CD4+ T helper cells in sha** localized memory
B cell and CD8+ T cell immunity in the mucosal tissues. Here, we report that lung T helper …
B cell and CD8+ T cell immunity in the mucosal tissues. Here, we report that lung T helper …
[HTML][HTML] Tissue resident memory T cells in the respiratory tract
MZM Zheng, LM Wakim - Mucosal immunology, 2022 - Elsevier
Owing to their capacity to rapidly spread across the population, airborne pathogens
represent a significant risk to global health. Indeed, several of the past major global …
represent a significant risk to global health. Indeed, several of the past major global …
Peripheral CD4+ T cell subsets and antibody response in COVID-19 convalescent individuals
F Gong, Y Dai, T Zheng, L Cheng… - The Journal of …, 2020 - Am Soc Clin Investig
BACKGROUND Marked progress is achieved in understanding the physiopathology of
coronavirus disease 2019 (COVID-19), which caused a global pandemic. However, the …
coronavirus disease 2019 (COVID-19), which caused a global pandemic. However, the …