Striae distansae (SD) or stretch marks are very common, asymptomatic, skin condition
frequently seen among females between 5 to 50 years of ages. It often causes cosmetic …

Acute aortic dissection (AAD) is a life-threatening disease with an incidence of about 2.6–3.6
cases per 100,000/year. Depending on the site of rupture, AAD is classified as Stanford-A …

Background—It has been shown that losartan reduces aortic dilatation in patients with
Marfan syndrome. However, treatment response is highly variable. This study investigates …

Background Marfan syndrome (MFS) is a genetically determined systemic connective tissue
disorder, caused by a mutation in the FBN1 gene. In MFS mainly the cardiovascular …

Background Marfan syndrome (MFS) is a systemic connective tissue disorder with life-
threatening manifestations affecting the ascending aorta. MFS is caused by dominant …

Background We retrospectively analyzed 25 years of experiences with the button Bentall
procedure in patients with aortic root pathologies. Even though this procedure has become …

The subject matter of this chapter comprises the major acquired disorders that affect mainly
collagen and elastic tissue. The connective tissue of normal skin is discussed elsewhere …

Background High-sensitivity cardiac troponin is the most specific and sensitive biomarker of
myocardial injury. However, no study has investigated whether the early concentration of …

Abstract Background Striae Distensae (SD) is a common dermatological lesion. The
mechanism of formation is unclear, the prevailing theory is mechanical pulling of the skin …

Background Clinical evidence suggests that the currently recommended approach to
estimate the risk of aortic dissection in Marfan syndrome (MFS) is not reliable enough …