RDP4 is the latest version of recombination detection program (RDP), a Windows computer
program that implements an extensive array of methods for detecting and visualising …

Highlights•Multipartite and segmented viruses are members of∼ 11% of classified virus
genera.•Segmented viruses with semi-infectious particles have higher propensity to …

Predicting the evolution of virus host range has proven to be extremely difficult, in part
because of the sheer diversity of viruses, each with unique biology and ecological …

The latent reservoir is a major barrier to HIV eradication. Reservoir size is emerging as an
important biomarker to assess the likelihood of HIV remission in the absence of antiretroviral …

Recombination is an important feature of HIV evolution, occurring both within and between
the major branches of diversity (subtypes). The Ugandan epidemic is primarily composed of …

The influenza-A virus (IAV) causes seasonal epidemics and presents a pandemic risk with
the possibility of genetic re-assortment, allowing the emergence of new strains. The …

The Congo Basin region is believed to be the site of the cross-species transmission event
that yielded HIV-1 group M (HIV-1M). It is thus likely that the virus has been present and …

The low frequency of HIV-1 recombinants within entire viral populations in both individual
patients and culture-based infection models impedes investigation of the underlying factors …

Recombination between different HIV-1 group M (HIV-1M) subtypes is a major contributor to
the ongoing genetic diversification of HIV-1M. However, it remains unclear whether the …

Abstract HIV-1 and HIV-2 both cause AIDS in humans, and both originated in nonhuman
primates in Africa before several cross-species transmission events introduced them into …