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[HTML][HTML] Ursolic acid and its derivatives as bioactive agents
Non-communicable diseases (NCDs) such as cancer, diabetes, and chronic respiratory and
cardiovascular diseases continue to be threatening and deadly to human kind. Resistance …
cardiovascular diseases continue to be threatening and deadly to human kind. Resistance …
[HTML][HTML] Ursolic acid—a pentacyclic triterpenoid with a wide spectrum of pharmacological activities
Ł Woźniak, S Skąpska, K Marszałek - Molecules, 2015 - mdpi.com
Ursolic acid (UA) is a natural terpene compound exhibiting many pharmaceutical properties.
In this review the current state of knowledge about the health-promoting properties of this …
In this review the current state of knowledge about the health-promoting properties of this …
A comprehensive analysis of the composition, health benefits, and safety of apple pomace
Apple processing results in peel, stem, seeds, and pulp being left as a waste product known
as apple pomace. This review comprehensively assessed apple pomace composition for …
as apple pomace. This review comprehensively assessed apple pomace composition for …
Ursolic acid from apple pomace and traditional plants: A valuable triterpenoid with functional properties
ST Cargnin, SB Gnoatto - Food Chemistry, 2017 - Elsevier
Apple juice production generates a large amount of residue comprising mainly peels, seeds,
and pulp, known as apple pomace. In the global context, Brazil ranks 11th in apple …
and pulp, known as apple pomace. In the global context, Brazil ranks 11th in apple …
Chemical derivatization of natural products: Semisynthesis and pharmacological aspects-A decade update
Natural products and their semisynthetic derivatives continue to be an important source of
potential drug leads. Natural products and their analogues structures possess the …
potential drug leads. Natural products and their analogues structures possess the …
Design and synthesis of pentacyclic triterpene conjugates and their use in medicinal research
J Hodon, L Borkova, J Pokorny, A Kazakova… - European journal of …, 2019 - Elsevier
Triterpenoids are natural products from plants and many other organisms that have various
biological activities, such as antitumor, antiviral, antimicrobial, and protective activities. This …
biological activities, such as antitumor, antiviral, antimicrobial, and protective activities. This …
Selected plant triterpenoids and their amide derivatives in cancer treatment: A review
Z Özdemir, Z Wimmer - Phytochemistry, 2022 - Elsevier
Medicinal plants have been used to treat different diseases throughout the human history
namely in traditional medicine. Most of the plants mentioned in this review article belong …
namely in traditional medicine. Most of the plants mentioned in this review article belong …
Recent developments in the functionalization of betulinic acid and its natural analogues: a route to new bioactive compounds
JLC Sousa, CSR Freire, AJD Silvestre, AMS Silva - Molecules, 2019 - mdpi.com
Betulinic acid (BA) and its natural analogues betulin (BN), betulonic (BoA), and 23-
hydroxybetulinic (HBA) acids are lupane-type pentacyclic triterpenoids. They are present in …
hydroxybetulinic (HBA) acids are lupane-type pentacyclic triterpenoids. They are present in …
Betulinic acid alleviates non-alcoholic fatty liver by inhibiting SREBP1 activity via the AMPK–mTOR–SREBP signaling pathway
HY Quan, SJ Kim, HK Jo, GW Kim, SH Chung - Biochemical …, 2013 - Elsevier
Non-alcoholic fatty liver disease (NAFLD) is emerging as the most common liver disease in
industrialized countries. The discovery of food components that can ameliorate NAFLD is …
industrialized countries. The discovery of food components that can ameliorate NAFLD is …
Antimalarial naphthoquinones. Synthesis via click chemistry, in vitro activity, docking to PfDHODH and SAR of lapachol-based compounds
GC Brandão, FCR Missias, LM Arantes… - European journal of …, 2018 - Elsevier
Lapachol is an abundant prenyl naphthoquinone occurring in Brazilian Bignoniaceae that
was clinically used, in former times, as an antimalarial drug, despite its moderate effect …
was clinically used, in former times, as an antimalarial drug, despite its moderate effect …