Over the past decades, a large number of drugs as well as drug candidates with poor
dissolution characteristics have been witnessed, which invokes great interest in enabling …

The application of synthetic polymers as delivery systems of chemotherapy drugs has
opened a very prospective field for research in cancer therapy. Due to their unique and …

Purpose To understand the role of different surfactants, incorporated into amorphous solid
dispersions (ASDs) of ritonavir and copovidone, in terms of their impact on release, phase …

Numerous amorphous solid dispersion (ASD) formulations of celecoxib (CEL) have been
attempted for enhancing the solubility, dissolution rate, and in vivo pharmacokinetics via …

Amorphous solid dispersions (ASDs) have been proven to increase the bioavailability of
poorly soluble drugs. It is desirable that the ASD provide a rapid dissolution rate and a …

Apremilast, a BCS class IV drug, has minimal solubility in aqueous medium which results in
poor bioavailability. With an intention of enhancing the bioavailability, amorphous solid …

The present study focused on a new formulation approach to improving the solubility of
drugs with poor aqueous solubility. A hot melt extrusion (HME) process was applied to …

The understanding of amorphous solid dispersions has grown significantly in the past
decade. This is evident from the number of approved commercial amorphous solid …

The objectives of this work were to develop meloxicam based amorphous solid dispersion
through electrospinning technique and evaluate the effect of the polymeric matrix on the …

Co-amorphous systems have been developed to address the solubility challenge of poorly-
water soluble drugs. However, the dissolution rate of co-amorphous systems can be too fast …