Review of in silico models of cerebral blood flow in health and pathology
In this review, we provide a summary of the state-of-the-art in the in silico modelling of
cerebral blood flow (CBF) and its application in in silico clinical trials. CBF plays a key role in …
cerebral blood flow (CBF) and its application in in silico clinical trials. CBF plays a key role in …
Blood clot behaves as a poro-visco-elastic material
Mechanical properties of blood clots play a crucial role in hemostasis and embolization.
They are time-dependent and often described with viscoelastic models. But blood clots also …
They are time-dependent and often described with viscoelastic models. But blood clots also …
[HTML][HTML] Adhesive and cohesive fracture of blood clots: Experiments and modeling
Blood clots represent living materials composed of a polymer network and an abundance of
cells. They might fracture within the bulk material of the clot (cohesive fracture), at the …
cells. They might fracture within the bulk material of the clot (cohesive fracture), at the …
Combined stent-retriever and aspiration intra-arterial thrombectomy performance for fragmentable blood clots: A proof-of-concept computational study
Mechanical thrombectomy (MT) treatment of acute ischemic stroke (AIS) patients typically
involves use of stent retrievers or aspiration catheters alone or in combination. For in silico …
involves use of stent retrievers or aspiration catheters alone or in combination. For in silico …
Clots reveal anomalous elastic behavior of fiber networks
The adaptive mechanical properties of soft and fibrous biological materials are relevant to
their functionality. The emergence of the macroscopic response of these materials to …
their functionality. The emergence of the macroscopic response of these materials to …
Current Approaches and Methods to Understand Acute Ischemic Stroke Treatment Using Aspiration Thrombectomy
Acute ischemic stroke occurs when a blood clot occludes a cerebral artery. Mechanical
interventions, primarily stent retrievers and aspiration thrombectomy, are used currently for …
interventions, primarily stent retrievers and aspiration thrombectomy, are used currently for …
Hyperelasticity of Blood Clots: Bridging the Gap between Microscopic and Continuum Scales
The biomechanical properties of blood clots, which are dictated by their compositions and
micro-structures, play a critical role in determining their fates, ie, occlusion, persistency, or …
micro-structures, play a critical role in determining their fates, ie, occlusion, persistency, or …
[HTML][HTML] An elastic–viscoplastic model with non-affine deformation and rotation of a distribution of embedded fibres
A large deformation continuum model for an elastically isotropic visco-plastic matrix
reinforced by a distribution of fibres has been formulated. The fibre distribution is a …
reinforced by a distribution of fibres has been formulated. The fibre distribution is a …
Energy barriers govern catheter herniation during endovascular procedures: a 2.5 D vascular flow model analysis
MY Qiu, CB Suskin, MA Zayed… - Journal of the …, 2024 - royalsocietypublishing.org
Endovascular procedures rely on navigating guidewires, catheters and other devices
through tortuous vasculature to treat disease. A critical challenge in these procedures is …
through tortuous vasculature to treat disease. A critical challenge in these procedures is …
Computational analysis of effects of clot length on Acute ischemic stroke recanalization under different cyclic aspiration loading conditions
Acute ischemic stroke, the second leading cause of death worldwide, results from occlusion
of a cerebral artery by a blood clot. Application of cyclic aspiration using an aspiration …
of a cerebral artery by a blood clot. Application of cyclic aspiration using an aspiration …