The biology and role of CD44 in cancer progression: therapeutic implications
C Chen, S Zhao, A Karnad, JW Freeman - Journal of hematology & …, 2018 - Springer
CD44, a non-kinase transmembrane glycoprotein, is overexpressed in several cell types
including cancer stem cells and frequently shows alternative spliced variants that are …
including cancer stem cells and frequently shows alternative spliced variants that are …
Pathobiology of Helicobacter pylori–induced gastric cancer
M Amieva, RM Peek Jr - Gastroenterology, 2016 - Elsevier
Colonization of the human stomach by Helicobacter pylori and its role in causing gastric
cancer is one of the richest examples of a complex relationship among human cells …
cancer is one of the richest examples of a complex relationship among human cells …
Scavenger receptors in host defense: from functional aspects to mode of action
Scavenger receptors belong to a superfamily of proteins that are structurally heterogeneous
and encompass the miscellaneous group of transmembrane proteins and soluble secretory …
and encompass the miscellaneous group of transmembrane proteins and soluble secretory …
Single-cell transcriptomics uncovers EGFR signaling-mediated gastric progenitor cell differentiation in stomach homeostasis
H Takada, Y Sasagawa, M Yoshimura… - Nature …, 2023 - nature.com
Defects in gastric progenitor cell differentiation are associated with various gastric disorders,
including atrophic gastritis, intestinal metaplasia, and gastric cancer. However, the …
including atrophic gastritis, intestinal metaplasia, and gastric cancer. However, the …
Claudins and gastric cancer: an overview
I Hashimoto, T Oshima - Cancers, 2022 - mdpi.com
Simple Summary Gastric cancer (GC) is one of the most common cancers and the third
leading cause of cancer deaths worldwide, with a high frequency of recurrence and …
leading cause of cancer deaths worldwide, with a high frequency of recurrence and …
Cellular plasticity, reprogramming, and regeneration: metaplasia in the stomach and beyond
The mucosa of the body of the stomach (ie, the gastric corpus) uses 2 overlap**, depth-
dependent mechanisms to respond to injury. Superficial injury heals via surface cells with …
dependent mechanisms to respond to injury. Superficial injury heals via surface cells with …
The role of CD44 in disease pathophysiology and targeted treatment
AR Jordan, RR Racine, MJP Hennig… - Frontiers in …, 2015 - frontiersin.org
The cell-surface glycoprotein CD44 is involved in a multitude of important physiological
functions including cell proliferation, adhesion, migration, hematopoiesis, and lymphocyte …
functions including cell proliferation, adhesion, migration, hematopoiesis, and lymphocyte …
A novel human gastric primary cell culture system for modelling Helicobacter pylori infection in vitro
P Schlaermann, B Toelle, H Berger, SC Schmidt… - Gut, 2016 - gut.bmj.com
Background and aims Helicobacter pylori is the causative agent of gastric diseases and the
main risk factor in the development of gastric adenocarcinoma. In vitro studies with this …
main risk factor in the development of gastric adenocarcinoma. In vitro studies with this …
Hyaluronan, inflammation, and breast cancer progression
Breast cancer-induced inflammation in the tumor reactive stroma supports invasion and
malignant progression and is contributed to by a variety of host cells including macrophages …
malignant progression and is contributed to by a variety of host cells including macrophages …
Characterization of biomarkers of tumorigenic and chemoresistant cancer stem cells in human gastric carcinoma
Purpose: Gastric carcinomas are heterogeneous, and the current therapy remains
essentially based on surgery with conventional chemotherapy and radiotherapy. This study …
essentially based on surgery with conventional chemotherapy and radiotherapy. This study …