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Mechanisms underlying dose-limiting toxicities of conventional chemotherapeutic agents
MA Manavi, MH Fathian Nasab… - Journal of …, 2024 - Taylor & Francis
Dose-limiting toxicities (DLTs) are severe adverse effects that define the maximum tolerated
dose of a cancer drug. In addition to the specific mechanisms of each drug, common …
dose of a cancer drug. In addition to the specific mechanisms of each drug, common …
Pharmacological updates of nifuroxazide: promising preclinical effects and the underlying molecular mechanisms
Nifuroxazide (NFX) is a safe nitrofuran antibacterial drug used clinically to treat acute
diarrhea and infectious traveler diarrhea or colitis. Recent studies revealed that NFX …
diarrhea and infectious traveler diarrhea or colitis. Recent studies revealed that NFX …
Unveiling the capability of novel cobalt/barium stannate nanoparticles embedded functionalized MWCNTs nanocomposite for electrochemical investigation of …
Nifuroxazide (NFR) is a class of synthetic broad-spectrum antibiotics and recently was
proven to have anticancer properties, which are widely used to treat infectious diarrhea and …
proven to have anticancer properties, which are widely used to treat infectious diarrhea and …
[HTML][HTML] Mirtazapine, an atypical antidepressant, mitigates lung fibrosis by suppressing NLPR3 inflammasome and fibrosis-related mediators in endotracheal …
Idiopathic pulmonary fibrosis (IPF) is a progressive and irreversible lung disease with a poor
prognosis. There is currently no definitive cure for IPF. The present study establishes a …
prognosis. There is currently no definitive cure for IPF. The present study establishes a …
Pregnancy and COVID-19: high or low risk of vertical transmission
Abstract Coronavirus disease 19 (COVID-19) is an infectious disease caused by severe
acute respiratory syndrome 2 (SARS-CoV-2). Throughout the pandemic, evidence on the …
acute respiratory syndrome 2 (SARS-CoV-2). Throughout the pandemic, evidence on the …
Revolutionizing the treatment of idiopathic pulmonary fibrosis: From conventional therapies to advanced drug delivery systems
S Singh, S Wairkar - AAPS PharmSciTech, 2024 - Springer
Idiopathic pulmonary fibrosis (IPF) is a chronic and progressive interstitial lung disease that
has been well-reported in the medical literature. Its incidence has risen, particularly in light …
has been well-reported in the medical literature. Its incidence has risen, particularly in light …
Nifuroxazide mitigates doxorubicin-induced cardiovascular injury: Insight into oxidative/NLRP3/GSDMD-mediated pyroptotic signaling modulation
Doxorubicin (DOX) is a widely used powerful anthracycline for treatment of many varieties of
malignancies; however its cumulative and dose-dependent cardio-toxicity has been limited …
malignancies; however its cumulative and dose-dependent cardio-toxicity has been limited …
[HTML][HTML] Pimitespib, an HSP90 inhibitor, augments nifuroxazide-induced disruption in the IL-6/STAT3/HIF-1α autocrine loop in rats with bleomycin-challenged lungs …
Idiopathic pulmonary fibrosis is a fatal lung disorder in which the etiology and pathogenesis
are still unobvious. Effective treatments are urgently needed considering that lung …
are still unobvious. Effective treatments are urgently needed considering that lung …
Unlocking the potential of nanocarrier-mediated mRNA delivery across diverse biomedical frontiers: A comprehensive review
Messenger RNA (mRNA) has gained marvelous attention for managing and preventing
various conditions like cancer, Alzheimer's, infectious diseases, etc. Due to the quick …
various conditions like cancer, Alzheimer's, infectious diseases, etc. Due to the quick …
Progress and challenges of lyotropic liquid crystalline nanoparticles for innovative therapies
AVP Silvestrini, BW Debiasi, FG Praca… - International Journal of …, 2022 - Elsevier
Since the late 20th century, we have witnessed a growing and substantial advance in
nanomedicine, in part due to the development of multifunctional and multimodal …
nanomedicine, in part due to the development of multifunctional and multimodal …