Using a three-dimensional model of cell monolayers, we study the spatial organization of
active stress chains as the monolayer transitions from a solid to a liquid state. The critical …

Multiphase field models have emerged as an important computational tool for understanding
biological tissue while resolving single-cell properties. While they have successfully …

Cells not only have self-motility by crawling but are also capable of other types of active
motions like periodic contraction or pulsation. In this work, by using the Voronoi cell model …

Complex tissue flows in epithelia are driven by intra-and inter-cellular processes that
generate, maintain, and coordinate mechanical forces. There has been growing evidence …

Active emulsions and liquid crystalline shells are intriguing and experimentally realisable
types of topological matter. Here we numerically study the morphology and spatiotemporal …

Three-dimensional tissue spheroids are a key building block in biofabrication, yet the link
between their material properties and active mechanics of individual cells is not fully …

Collective epithelial migration leverages on topological rearrangements of the intercellular
junctions, which allow cells to intercalate without loosing confluency. In silico studies have …

In confluent cell monolayers, patterns of cell forces and motion are systematically altered
near topological defects in cell shape. In turn, defects have been proposed to alter cell …

Complex tissue flows in epithelia are driven by intra-and inter-cellular processes that
generate, maintain, and coordinate mechanical forces. There has been growing evidence …

Complex tissue flows in epithelia are driven by intra-and inter-cellular processes that
generate, maintain, and coordinate mechanical forces. There has been growing evidence …