Multiple system atrophy (MSA) is a progressive neurodegenerative disorder characterised
by a variable combination of autonomic failure, levodopa-unresponsive parkinsonism …

Although commonly known as movement disorders, progressive supranuclear palsy (PSP)
and corticobasal syndrome (CBS) may present with changes in speech and language …

To better understand the pathological and phenotypic heterogeneity of progressive
supranuclear palsy and the links between the two, we applied a novel unsupervised …

Background Antimuscarinics are often used for treatment of overactive bladder (OAB), but
exposure to medications such as antimuscarinics that have anticholinergic properties has …

Fatigue is a common non-motor symptom in Parkinson's disease (PD), but even so, it may
still be underdiagnosed or misdiagnosed in current practice due to its non-specific …

Abstract The International Parkinson's and Movement Disorder Society (MDS) criteria for
progressive supranuclear palsy (PSP) have broadened the clinical spectrum of the disease …

Background There is currently no undisputed, validated, clinically meaningful measure for
deficits in the broad spectrum of PSP phenotypes. Objective To develop a scale to monitor …

Abstract Background: The Montreal Cognitive Assessment (MoCA) is a sensitive screening
instrument for mild neurocognitive disorder (mild NCD). However, cut-off scores and …

Progressive supranuclear palsy causes diverse clinical presentations, including classical
Richardson's syndrome and several variant phenotypes. Clinical trials of disease-modifying …

Abstract Dementia in Lewy Body Diseases (Parkinson's disease and dementia with Lewy
Bodies) affects progression of disabilities, quality of life and well-being. Understanding its …