Whole blood, as one of the most significant biological fluids, provides critical information for
health management and disease monitoring. Over the past 10 years, advances in …

This white paper discusses prospects for advancing hyperpolarization technology to better
understand cancer metabolism, identify current obstacles to HP (hyperpolarized) 13 C …

The imaging and clinical management of patients with brain tumor continue to evolve over
time and now heavily rely on physiologic imaging in addition to high-resolution structural …

NMR spectroscopy has been applied to cells and tissues analysis since its beginnings, as
early as 1950. We have attempted to gather here in a didactic fashion the broad diversity of …

Mutations in isocitrate dehydrogenase 1 and 2 (IDH1 and IDH2) are key events in the
development of glioma, acute myeloid leukemia (AML), chondrosarcoma, intrahepatic …

This review focuses on metabolomics from an NMR point of view. It attempts to cover the
broad scope of metabolomics and describes the NMR experiments that are most suitable for …

Preoperative clinical MRI protocols for gliomas, brain tumors with dismal outcomes due to
their infiltrative properties, still rely on conventional structural MRI, which does not deliver …

Early detection and diagnostics are essential for the cure of cancer which has high mortality
rate globally. In recent decades, various methods such as mammography, computed …

Hyperpolarized magnetic resonance allows for noninvasive measurements of biochemical
reactions in vivo. Although this technique provides a unique tool for assaying enzymatic …

Despite advances in surgery and adjuvant therapy, brain tumors represent one of the
leading causes of cancer‐related mortality and morbidity in both adults and children …