Advancing from statistical associations of complex traits with genetic markers to
understanding the functional genetic variants that influence traits is often a complex process …

Here, we provide an update of our review on homeobox genes that we wrote together with
Walter Gehring in 1994. Since then, comprehensive surveys of homeobox genes have …

Abstract JASPAR (https://jaspar. elixir. no/) is a widely-used open-access database
presenting manually curated high-quality and non-redundant DNA-binding profiles for …

Computational methods that model how gene expression of a cell is influenced by
interacting cells are lacking. We present NicheNet (https://github. com/saeyslab/nichenetr), a …

The growing application of gene expression profiling demands powerful yet user-friendly
bioinformatics tools to support systems-level data understanding. NetworkAnalyst was first …

With the dramatic development of single-cell RNA sequencing (scRNA-seq) technologies,
the systematic decoding of cell-cell communication has received great research interest. To …

Abstract JASPAR (http://jaspar. genereg. net) is an open-access database of curated, non-
redundant transcription factor (TF)-binding profiles stored as position frequency matrices …

Developmental processes underlying normal tissue regeneration have been implicated in
cancer, but the degree of their enactment during tumor progression and under the selective …

Cohesin catalyses the folding of the genome into loops that are anchored by CTCF. The
molecular mechanism of how cohesin and CTCF structure the 3D genome has remained …

Major advances in crop yields are needed in the coming decades. However, plant breeding
is currently limited by incremental improvements in quantitative traits that often rely on …