Role of gut microbiota and nutrients in amyloid formation and pathogenesis of Alzheimer disease

F Pistollato, S Sumalla Cano, I Elio… - Nutrition …, 2016 - academic.oup.com
It has been hypothesized that alterations in the composition of the gut microbiota might be
associated with the onset of certain human pathologies, such as Alzheimer disease, a …

Neurobiological effects of gallic acid: Current perspectives

MS Bhuia, MM Rahaman, T Islam, MH Bappi… - Chinese Medicine, 2023 - Springer
Gallic acid (GA) is a phenolic molecule found naturally in a wide range of fruits as well as in
medicinal plants. It has many health benefits due to its antioxidant properties. This study …

[HTML][HTML] The potential health benefits of gallic acid: Therapeutic and food applications

M Hadidi, R Liñán-Atero, M Tarahi, MC Christodoulou… - Antioxidants, 2024 - mdpi.com
Gallic acid (GA), a phenolic acid found in fruits and vegetables, has been consumed by
humans for centuries. Its extensive health benefits, such as antimicrobial, antioxidant …

Gallic acid: review of the methods of determination and quantification

FHA Fernandes, HRN Salgado - Critical reviews in analytical …, 2016 - Taylor & Francis
ABSTRACT Gallic acid (3, 4, 5 trihydroxybenzoic acid) is a secondary metabolite present in
most plants. This metabolite is known to exhibit a range of bioactivities including antioxidant …

Targeting amyloid aggregation: an overview of strategies and mechanisms

S Giorgetti, C Greco, P Tortora, FA Aprile - International journal of …, 2018 - mdpi.com
Amyloids result from the aggregation of a set of diverse proteins, due to either specific
mutations or promoting intra-or extra-cellular conditions. Structurally, they are rich in …

Inhibition of protein misfolding and aggregation by natural phenolic compounds

Z Dhouafli, K Cuanalo-Contreras, EA Hayouni… - Cellular and molecular …, 2018 - Springer
Protein misfolding and aggregation into fibrillar deposits is a common feature of a large
group of degenerative diseases affecting the central nervous system or peripheral organs …

Grapes (Vitis vinifera) as a Potential Candidate for the Therapy of the Metabolic Syndrome

M Akaberi, H Hosseinzadeh - Phytotherapy Research, 2016 - Wiley Online Library
Metabolic syndrome is associated with several disorders, including hypertension, diabetes,
hyperlipidemia as well as cardiovascular diseases and stroke. Plant‐derived polyphenols …

Dietary plant polyphenols as the potential drugs in neurodegenerative diseases: current evidence, advances, and opportunities

L Yan, MS Guo, Y Zhang, L Yu, JM Wu… - Oxidative Medicine …, 2022 - Wiley Online Library
Neurodegenerative diseases, including Alzheimer's disease (AD), Parkinson's disease (PD),
and Huntington's disease (HD), are characterized by the progressive degeneration of …

Exploring the multifaceted neuroprotective actions of gallic acid: A review

S Shabani, Z Rabiei, H Amini-Khoei - International Journal of Food …, 2020 - Taylor & Francis
Much attention has been recently given to the effect of diet compounds on physical and
mental health. Gallic acid is a phenolic compound with antioxidant activity. This compound is …

Gallic acid disruption of Aβ1–42 aggregation rescues cognitive decline of APP/PS1 double transgenic mouse

M Yu, X Chen, J Liu, Q Ma, Z Zhuo, H Chen… - Neurobiology of …, 2019 - Elsevier
Alzheimer's disease (AD) treatment represents one of the largest unmet medical needs.
Develo** small molecules targeting Aβ aggregation is an effective approach to prevent …