Metabolic effects of dietary nitrate in health and disease

JO Lundberg, M Carlström, E Weitzberg - Cell metabolism, 2018 - cell.com
Nitric oxide (NO), generated from L-arginine and oxygen by NO synthases, is a pleiotropic
signaling molecule involved in cardiovascular and metabolic regulation. More recently, an …

The noncanonical pathway for in vivo nitric oxide generation: the nitrate-nitrite-nitric oxide pathway

V Kapil, RS Khambata, DA Jones, K Rathod… - Pharmacological …, 2020 - Elsevier
In contrast to nitric oxide, which has well established and important roles in the regulation of
blood flow and thrombosis, neurotransmission, the normal functioning of the genitourinary …

A practical guide for induction of type-2 diabetes in rat: Incorporating a high-fat diet and streptozotocin

S Gheibi, K Kashfi, A Ghasemi - Biomedicine & pharmacotherapy, 2017 - Elsevier
Prevalence of diabetes, a serious public health problem is rapidly increasing worldwide.
Type-2 diabetes is the common form of diabetes characterized by insulin resistance and …

Kombucha reduces hyperglycemia in type 2 diabetes of mice by regulating gut microbiota and its metabolites

S Xu, Y Wang, J Wang, W Geng - Foods, 2022 - mdpi.com
Kombucha, which is rich in tea polyphenols and organic acid, is a kind of acidic tea soup
beverage fermented by acetic acid bacteria, yeasts, lactic acid bacteria. Kombucha has …

Regulation of vascular tone homeostasis by NO and H2S: Implications in hypertension

S Gheibi, S Jeddi, K Kashfi, A Ghasemi - Biochemical pharmacology, 2018 - Elsevier
Nitric oxide (NO) and hydrogen sulfide (H 2 S) are two gasotransmitters that are produced in
the vasculature and contribute to the regulation of vascular tone. NO and H 2 S are …

From nitrate to NO: potential effects of nitrate-reducing bacteria on systemic health and disease

H Liu, Y Huang, M Huang, M Wang, Y Ming… - European Journal of …, 2023 - Springer
Current research has described improving multisystem disease and organ function through
dietary nitrate (DN) supplementation. They have provided some evidence that these floras …

Obesity, type-2 diabetes and cancer: mechanistic insights

K Kashfi, CL Rosen, M Aslan - Critical Reviews™ in …, 2019 - dl.begellhouse.com
Obesity leads to many diseases including hypercholesterolemia, type-2 diabetes,
hypertension, cardiovascular disease, and cancer. It is the fastest-growing lethal disease in …

Effects of long-term nitrate supplementation on carbohydrate metabolism, lipid profiles, oxidative stress, and inflammation in male obese type 2 diabetic rats

S Gheibi, S Jeddi, M Carlström, H Gholami, A Ghasemi - Nitric Oxide, 2018 - Elsevier
Purpose Supplementation with inorganic nitrate to boost the nitrate-nitrite-nitric oxide (NO)
pathway, may act as a potential therapeutic agent in diabetes. The aim of this study was to …

Anti-obesity and anti-diabetic effects of nitrate and nitrite

A Ghasemi, S Jeddi - Nitric oxide, 2017 - Elsevier
Prevalence of obesity is increasing worldwide and type 2 diabetes to date is the most
devastating complication of obesity. Decreased nitric oxide bioavailability is a feature of …

Hypoxia in obesity and diabetes: potential therapeutic effects of hyperoxia and nitrate

R Norouzirad, P González-Muniesa… - … medicine and cellular …, 2017 - Wiley Online Library
The prevalence of obesity and diabetes is increasing worldwide. Obesity and diabetes are
associated with oxidative stress, inflammation, endothelial dysfunction, insulin resistance …