Gases like H2, N2, CO2, and CO are increasingly recognized as critical feedstock in “green”
energy conversion and as sources of nitrogen and carbon for the agricultural and chemical …

The reaction takes place at a specialized metal center that dramatically increases the acidity
of H2 and leads to a heterolytic splitting of the molecule which is strongly accelerated by the …

It was once widely held that nearly all reactions in biology were catalyzed via mechanisms
involving paired electron species. Beginning approximately 40 years ago, this paradigm was …

Abstract The [FeFe]-and [NiFe]-hydrogenases catalyze the formal interconversion between
hydrogen and protons and electrons, possess characteristic non-protein ligands at their …

Reduced nicotinamide adenine dinucleotide phosphate (NADPH) is an essential electron
donor in all organisms. It provides the reducing power that drives numerous anabolic …

There are currently intensive global research efforts aimed at increasing and modifying the
accumulation of lipids, alcohols, hydrocarbons, polysaccharides, and other energy storage …

Decelerating global warming is one of the predominant challenges of our time and will
require conversion of CO 2 to usable products and commodity chemicals. Of particular …

If the atmosphere of the early Earth was hydrogen-rich, 1 it is reasonable to think that
hydrogenases, the enzymes enabling cells to use molecular hydrogen, were probably …

This review describes the functions, structures, and mechanisms of nine nickel-containing
enzymes: glyoxalase I, acireductone dioxygenase, urease, superoxide dismutase,[NiFe] …

Nickel enzymes, present in archaea, bacteria, plants, and primitive eukaryotes are divided
into redox and nonredox enzymes and play key functions in diverse metabolic processes …