Progress in brain targeting drug delivery system by nasal route

AR Khan, M Liu, MW Khan, G Zhai - Journal of Controlled Release, 2017 - Elsevier
The blood–brain barrier (BBB) restricts the transport of potential therapeutic moieties to the
brain. Direct targeting the brain via olfactory and trigeminal neural pathways by passing the …

Current approaches in lipid-based nanocarriers for oral drug delivery

M Plaza-Oliver, MJ Santander-Ortega… - Drug delivery and …, 2021 - Springer
Lipid-based nanocarriers have gained much interest as carriers of drugs with poor oral
bioavailability because of their remarkable advantages like low toxicity, affordable scale-up …

Application of various types of liposomes in drug delivery systems

M Alavi, N Karimi, M Safaei - Advanced pharmaceutical …, 2017 - pmc.ncbi.nlm.nih.gov
Liposomes, due to their various forms, require further exploration. These structures can
deliver both hydrophilic and hydrophobic drugs for cancer, antibacterial, antifungal …

Lipid based nanocarriers: a translational perspective

DK Mishra, R Shandilya, PK Mishra - … : Nanotechnology, Biology and …, 2018 - Elsevier
Over the recent couple of decades, pharmaceutical field has embarked most phenomenal
noteworthy achievements in the field of medications as well as drug delivery. The rise of …

Liposomes as Potential Drug Carrier Systems for Drug

M Çağdaş, AD Sezer, S Bucak - Application of nanotechnology in …, 2014 - books.google.com
Lipids are amphiphilic molecules, where one part of the molecule is water-loving
(hydrophilic) and the other water-hating (hydrophobic). When lipids are placed in contact …

Methotrexate: a detailed review on drug delivery and clinical aspects

ZA Khan, R Tripathi, B Mishra - Expert opinion on drug delivery, 2012 - Taylor & Francis
Introduction: Uses of methotrexate (MTX) are well established for the treatment of various
types of malignancy, psoriasis, rheumatological diseases and the medical termination of …

Liposomal delivery systems for intestinal lymphatic drug transport

H Ahn, JH Park - Biomaterials research, 2016 - spj.science.org
Intestinal lymphatic drug delivery has been widely studied because drugs can bypass the
first-pass metabolism in the liver via the lymphatic route, which increases oral bioavailability …

Multifaceted applications of bile salts in pharmacy: an emphasis on nanomedicine

YSR Elnaggar - International journal of nanomedicine, 2015 - Taylor & Francis
The human body has long provided pharmaceutical science with biomaterials of interesting
applications. Bile salts (BSs) are biomaterials reminiscent of traditional surfactants with …

Identifying lipidic emulsomes for improved oxcarbazepine brain targeting: In vitro and rat in vivo studies

GM El-Zaafarany, ME Soliman, S Mansour… - International journal of …, 2016 - Elsevier
Lipid-based nanovectors offer effective carriers for brain delivery by improving drug potency
and reducing off-target effects. Emulsomes are nano-triglyceride (TG) carriers formed of lipid …

[HTML][HTML] Development and evaluation of novel leflunomide SPION bioemulsomes for the intra-articular treatment of arthritis

H Abbas, HA Gad, NS El Sayed, LA Rashed… - Pharmaceutics, 2022 - mdpi.com
Systemic treatments for rheumatoid arthritis are associated with many side effects. This study
aimed to minimize the side effects associated with the systemic administration of leflunomide …