The unique immunological and microbial aspects of pregnancy
The comparison of the immunological state of pregnancy to an immunosuppressed host–
graft model continues to lead research and clinical practice to ill-defined approaches. This …
graft model continues to lead research and clinical practice to ill-defined approaches. This …
Viral infections during pregnancy
M Silasi, I Cardenas, JY Kwon, K Racicot… - American journal of …, 2015 - Wiley Online Library
Viral infections during pregnancy have long been considered benign conditions with a few
notable exceptions, such as herpes virus. The recent Ebola outbreak and other viral …
notable exceptions, such as herpes virus. The recent Ebola outbreak and other viral …
Classification, functions, and clinical relevance of extracellular vesicles
Both eukaryotic and prokaryotic cells release small, phospholipid-enclosed vesicles into
their environment. Why do cells release vesicles? Initial studies showed that eukaryotic …
their environment. Why do cells release vesicles? Initial studies showed that eukaryotic …
Host-and microbiota-derived extracellular vesicles, immune function, and disease development
Extracellular vesicles (EVs) are blebs of either plasma membrane or intracellular
membranes carrying a cargo of proteins, nucleic acids, and lipids. EVs are produced by …
membranes carrying a cargo of proteins, nucleic acids, and lipids. EVs are produced by …
Methodologies to isolate and purify clinical grade extracellular vesicles for medical applications
The use of extracellular vesicles (EV) in nano drug delivery has been demonstrated in many
previous studies. In this study, we discuss the sources of extracellular vesicles, including …
previous studies. In this study, we discuss the sources of extracellular vesicles, including …
Exosomes for drug delivery—a novel application for the mesenchymal stem cell
Exosomes are the most extensively characterized class of secreted membrane vesicles that
carry proteins and RNAs for intercellular communication. They are increasingly seen as …
carry proteins and RNAs for intercellular communication. They are increasingly seen as …
Exosomes as intercellular signaling organelles involved in health and disease: basic science and clinical applications
Cell to cell communication is essential for the coordination and proper organization of
different cell types in multicellular systems. Cells exchange information through a multitude …
different cell types in multicellular systems. Cells exchange information through a multitude …
Membrane microparticles: two sides of the coin
B Hugel, MC Martínez, C Kunzelmann… - …, 2005 - journals.physiology.org
Microparticles are plasma membrane-derived vesicles shed from stimulated cells, in the
broad sense of the term. Their presence is interpreted by proximal or remote cells in …
broad sense of the term. Their presence is interpreted by proximal or remote cells in …
Exosomes secreted by human placenta carry functional Fas ligand and TRAIL molecules and convey apoptosis in activated immune cells, suggesting exosome …
AC Stenqvist, O Nagaeva, V Baranov… - The Journal of …, 2013 - journals.aai.org
Apoptosis is crucially important in mediating immune privilege of the fetus during pregnancy.
We investigated the expression and in vitro apoptotic activity of two physiologically relevant …
We investigated the expression and in vitro apoptotic activity of two physiologically relevant …
Placental apoptosis in health and disease
AN Sharp, AEP Heazell, IP Crocker… - American journal of …, 2010 - Wiley Online Library
Citation Sharp AN, Heazell AEP, Crocker IP, Mor G. Placental apoptosis in health and
disease. Am J Reprod Immunol 2010; 64: 159–169 Apoptosis, programmed cell death, is an …
disease. Am J Reprod Immunol 2010; 64: 159–169 Apoptosis, programmed cell death, is an …