The pyroptotic role of Caspase-3/GSDME signalling pathway among various cancer: A Review

AA Bhat, R Thapa, O Afzal, N Agrawal… - International journal of …, 2023 - Elsevier
Cytotoxic drugs have long been recognised to kill cancer cells through apoptosis. According
to a current study, pyroptosis inhibits cell proliferation and shrinks tumors. Pyroptosis and …

[HTML][HTML] Targeted therapy for breast cancer: An overview of drug classes and outcomes

AT Jacobs, DM Castaneda-Cruz, MM Rose… - Biochemical …, 2022 - Elsevier
The last 25 years have seen significant growth in new therapeutic options for breast cancer,
termed targeted therapies based on their ability to block specific pathways known to drive …

Breast cancer mortality in 500 000 women with early invasive breast cancer diagnosed in England, 1993-2015: population based observational cohort study

C Taylor, P McGale, J Probert, J Broggio, J Charman… - Bmj, 2023 - bmj.com
Objectives To describe long term breast cancer mortality among women with a diagnosis of
breast cancer in the past and estimate absolute breast cancer mortality risks for groups of …

[HTML][HTML] Cuprous oxide nanocomposites with photothermal (PTT) and chemical dynamics (CDT) effects induce cuproptosis in breast cancer using the strategy of …

W Li, Y **ao, G Guo, J Peng, N Zhu, Z Chen, B Peng… - Nano Today, 2024 - Elsevier
Chemotherapy is a crucial adjuvant method of treating breast cancer, but it fails to achieve
preferable prognosis as the malignant cells eventually develop drug-resistance. Reduced …

[HTML][HTML] Application of nanoparticles in cancer treatment: a concise review

M Sell, AR Lopes, M Escudeiro, B Esteves… - Nanomaterials, 2023 - mdpi.com
Timely diagnosis and appropriate antitumoral treatments remain of utmost importance, since
cancer remains a leading cause of death worldwide. Within this context, nanotechnology …

circLIFR-007 reduces liver metastasis via promoting hnRNPA1 nuclear export and YAP phosphorylation in breast cancer

Y Zhang, Y Tan, J Yuan, H Tang, H Zhang, Y Tang… - Cancer Letters, 2024 - Elsevier
Cancer metastasis is the major cause of death in patients with breast cancer (BC). The liver
is a common site of breast cancer metastasis, and the 5-year survival rate of patients with …

DNMT3A and DNMT3B in breast tumorigenesis and potential therapy

X Man, Q Li, B Wang, H Zhang, S Zhang… - Frontiers in cell and …, 2022 - frontiersin.org
Breast cancer has become a leading cause of cancer-related deaths in women worldwide.
DNA methylation has been revealed to play an enormously important role in the …

[HTML][HTML] Role of mitochondria in doxorubicin-mediated cardiotoxicity: from molecular mechanisms to therapeutic strategies

T Wang, G **ng, T Fu, Y Ma, Q Wang, S Zhang… - Cell Stress and …, 2024 - Elsevier
This comprehensive review delves into the pivotal role of mitochondria in doxorubicin-
induced cardiotoxicity, a significant complication limiting the clinical use of this potent …

Molecular subtypes of breast cancer predicting clinical benefits of radiotherapy after breast-conserving surgery: a propensity-score-matched cohort study

SK Hung, HJ Yang, MS Lee, DW Liu, LC Chen… - Breast Cancer …, 2023 - Springer
Background Based on the molecular expression of cancer cells, molecular subtypes of
breast cancer have been applied to classify patients for predicting clinical outcomes and …

Circulating tumor DNA in the management of early-stage breast cancer

K Vlataki, S Antonouli, C Kalyvioti, E Lampri, S Kamina… - Cells, 2023 - mdpi.com
Liquid biopsies refer to the isolation and analysis of tumor-derived biological material from
body fluids, most commonly blood, in order to provide clinically valuable information for the …