Deciphering how the regulatory DNA sequence of a gene dictates its expression in
response to intra and extracellular cues is one of the leading challenges in modern …

The genomic revolution has indubitably brought about a paradigm shift in the field of
molecular biology, wherein we can sequence, write and re-write genomes. In spite of …

MicroRNAs bind to and regulate the abundance and activity of target messenger RNA
through sequestration, enhanced degradation, and suppression of translation. Although …

Regulation of transcription is a vital process in cells, but mechanistic details of this regulation
still remain elusive. The dominant approach to unravel the dynamics of transcriptional …

The post-transcriptional regulation of a protein by multiple small RNA molecules has been
formulated as a stochastic process. An approximate solution of the master equation shows …

MicroRNAs are small noncoding RNAs that regulate genes post-transciptionally by binding
and degrading target eukaryotic mRNAs. We use a quantitative model to study gene …

We study stochastic phenomena for a model of bacterial infection and neutrophils defense.
Sufficient conditions of stochastic permanence and extinction for the random model are …

The timings of several cellular events like cell lysis, cell division, or pore formation in
endosomes are regulated by the time taken for the relevant proteins to cross a threshold in …

In this paper we study an important global regulation mechanism of transcription of
biological cells using specific macro-molecules, 6S RNAs. The functional property of 6S …

Processive proteases, such as ClpXP in E. coli, are conserved enzyme assemblies that can
recognize and rapidly degrade proteins. These proteases are used for a number of …