Vascular inflammation is involved in the initiation and progression of atherosclerosis, and is
also present in hypertension-and diabetes-induced vascular complications. Angiotensin II …

Angiotensin (Ang) II-induced organ damage has fascinated students of hypertension since
the work of Wilson and Byrom. We are investigating a double transgenic rat (dTGR) model …

Hypertension is considered a low-grade inflammatory condition induced by various
proinflammatory cytokines, including tumor necrosis factor (TNF)-α. Recent studies have …

Background We investigated whether serum concentration of carboxy-terminal propeptide of
procollagen type I (PIP), a marker of collagen type I synthesis, can be used to assess the …

Abstract Aims Angiotensin II (ANG II)-induced inflammatory and oxidative stress responses
contribute to the pathogenesis of hypertension. In this study, we determined whether nuclear …

Losartan decreases plasma levels of TGF-β1 in transplant patients with chronic allograft
nephropathy. Background Chronic allograft nephropathy represents the principal cause of …

Background—Previous studies suggest that angiotensin II (Ang II) upregulates the
expression of tumor necrosis factor (TNF) in nonmyocyte cell types; however, the effect of …

Left ventricular hypertrophy in patients with hypertension is an important condition. It is
associated with significant mortality and carries increased risk for develo** nonfatal …

Abstract Angiotensin II (ANG II)-induced inflammatory and oxidative stress responses
contribute to the pathogenesis of hypertension. In this study, we determined whether renin …

Background/Aims: A recent study revealed that global overexpression of ET-1 causes a
slight reduction in systemic blood pressure. Moreover, heterozygous ET-1 knockout mice are …