Advances in progressive supranuclear palsy: new diagnostic criteria, biomarkers, and therapeutic approaches
Progressive supranuclear palsy (PSP), previously believed to be a common cause of
atypical parkinsonism, is now recognised as a range of motor and behavioural syndromes …
atypical parkinsonism, is now recognised as a range of motor and behavioural syndromes …
Evolving concepts in progressive supranuclear palsy and other 4-repeat tauopathies
M Stamelou, G Respondek, N Giagkou… - Nature Reviews …, 2021 - nature.com
Tauopathies are classified according to whether tau deposits predominantly contain tau
isoforms with three or four repeats of the microtubule-binding domain. Those in which four …
isoforms with three or four repeats of the microtubule-binding domain. Those in which four …
Redefining the multidimensional clinical phenotypes of frontotemporal lobar degeneration syndromes
The syndromes caused by frontotemporal lobar degeneration have highly heterogeneous
and overlap** clinical features. There has been great progress in the refinement of clinical …
and overlap** clinical features. There has been great progress in the refinement of clinical …
Radiological biomarkers for diagnosis in PSP: where are we and where do we need to be?
ABSTRACT PSP is a pathologically defined neurodegenerative tauopathy with a variety of
clinical presentations including typical Richardson's syndrome and other variant PSP …
clinical presentations including typical Richardson's syndrome and other variant PSP …
Sensitivity and specificity of diagnostic criteria for progressive supranuclear palsy
Abstract Background In 2017, the International Parkinson and Movement Disorder Society
put forward new clinical criteria for the diagnosis of PSP, recognizing diverse PSP …
put forward new clinical criteria for the diagnosis of PSP, recognizing diverse PSP …
Clinical, anatomical, and pathological features in the three variants of primary progressive aphasia: a review
Primary progressive aphasias (PPA) are neurodegenerative diseases clinically
characterized by an early and relatively isolated language impairment. Three main clinical …
characterized by an early and relatively isolated language impairment. Three main clinical …
A molecular pathology, neurobiology, biochemical, genetic and neuroimaging study of progressive apraxia of speech
Progressive apraxia of speech is a neurodegenerative syndrome affecting spoken
communication. Molecular pathology, biochemistry, genetics, and longitudinal imaging were …
communication. Molecular pathology, biochemistry, genetics, and longitudinal imaging were …
Primary progressive apraxia of speech: From recognition to diagnosis and care
JR Duffy, RL Utianski, KA Josephs - Aphasiology, 2021 - Taylor & Francis
Background Apraxia of speech (AOS) can be caused by neurodegenerative disease and
sometimes is its presenting sign (ie, primary progressive apraxia of speech, PPAOS). During …
sometimes is its presenting sign (ie, primary progressive apraxia of speech, PPAOS). During …
Retraining speech production and fluency in non-fluent/agrammatic primary progressive aphasia
The non-fluent/agrammatic variant of primary progressive aphasia (nfvPPA) presents with a
gradual decline in grammar and motor speech resulting from selective degeneration of …
gradual decline in grammar and motor speech resulting from selective degeneration of …
[HTML][HTML] Neuroimaging in frontotemporal dementia: heterogeneity and relationships with underlying neuropathology
Frontotemporal dementia encompasses a group of clinical syndromes defined
pathologically by degeneration of the frontal and temporal lobes. Historically, these …
pathologically by degeneration of the frontal and temporal lobes. Historically, these …