Metabolic channeling: predictions, deductions, and evidence

V Pareek, Z Sha, J He, NS Wingreen, SJ Benkovic - Molecular cell, 2021 - cell.com
With the elucidation of myriad anabolic and catabolic enzyme-catalyzed cellular pathways
crisscrossing each other, an obvious question arose: how could these networks operate with …

Almost all about citrulline in mammals

E Curis, I Nicolis, C Moinard, S Osowska, N Zerrouk… - Amino acids, 2005 - Springer
Citrulline (Cit, C 6 H 13 N 3 O 3), which is a ubiquitous amino acid in mammals, is strongly
related to arginine. Citrulline metabolism in mammals is divided into two fields: free citrulline …

Intraflagellar transport proteins 172, 80, 57, 54, 38, and 20 form a stable tubulin‐binding IFT‐B2 complex

M Taschner, K Weber, A Mourão, M Vetter… - The EMBO …, 2016 - embopress.org
Intraflagellar transport (IFT) relies on the IFT complex and is required for ciliogenesis. The
IFT‐B complex consists of 9–10 stably associated core subunits and six “peripheral” …

The nitrilase superfamily: classification, structure and function

HC Pace, C Brenner - Genome biology, 2001 - Springer
The nitrilase superfamily consists of thiol enzymes involved in natural product biosynthesis
and post-translational modification in plants, animals, fungi and certain prokaryotes. On the …

Channeling of substrates and intermediates in enzyme-catalyzed reactions

X Huang, HM Holden… - Annual review of …, 2001 - annualreviews.org
▪ Abstract The three-dimensional structures of tryptophan synthase, carbamoyl phosphate
synthetase, glutamine phosphoribosylpyrophosphate amidotransferase, and asparagine …

KH domain: one motif, two folds

NV Grishin - Nucleic acids research, 2001 - academic.oup.com
The K homology (KH) module is a widespread RNA-binding motif that has been detected by
sequence similarity searches in such proteins as heterogeneous nuclear ribonucleoprotein …

Enzymology of NAD+ homeostasis in man

G Magni, A Amici, M Emanuelli, G Orsomando… - Cellular and Molecular …, 2004 - Springer
This review describes the enzymes involved in human pyridine nucleotide metabolism
starting with a detailed consideration of their major kinetic, molecular and structural …

Allosteric pathways in imidazole glycerol phosphate synthase

I Rivalta, MM Sultan, NS Lee, GA Manley… - Proceedings of the …, 2012 - pnas.org
Protein allosteric pathways are investigated in the imidazole glycerol phosphate synthase
heterodimer in an effort to elucidate how the effector (PRFAR, N′-[(5′-phosphoribulosyl) …

Enzymology of Nad+ Synthesis

G Magni, A Amici, M Emanuelli… - … in Enzymology and …, 1999 - Wiley Online Library
Enzymology of NAD+ synthesis Page 147 ENZYMOLOGY OF NAD+ SYNTHESIS By
GIULIO MAGNI, ADOLFO AMICI, MONICA EMANUELLI, and NADIA RAFFAELLI, Istituto di …

Regulation of the nitrogen transfer pathway in the arbuscular mycorrhizal symbiosis: gene characterization and the coordination of expression with nitrogen flux

C Tian, B Kasiborski, R Koul, PJ Lammers… - Plant …, 2010 - academic.oup.com
The arbuscular mycorrhiza (AM) brings together the roots of over 80% of land plant species
and fungi of the phylum Glomeromycota and greatly benefits plants through improved …