Host-mycobiome metabolic interactions in health and disease
Fungal communities (mycobiome) have an important role in sustaining the resilience of
complex microbial communities and maintenance of homeostasis. The mycobiome remains …
complex microbial communities and maintenance of homeostasis. The mycobiome remains …
[HTML][HTML] Infection and inflammation: New perspectives on Alzheimer's disease
HE Whitson, C Colton, J El Khoury, D Gate… - Brain, behavior, & …, 2022 - Elsevier
Neuroinflammation has been recognized as a component of Alzheimer's Disease (AD)
pathology since the original descriptions by Alois Alzheimer and a role for infections in AD …
pathology since the original descriptions by Alois Alzheimer and a role for infections in AD …
[HTML][HTML] Uncovering the behaviour of ions in the gas-phase to predict the ion mobility separation of isomeric steroid compounds
Bile acids are steroid compounds involved in biological mechanisms of neurodegenerative
diseases making them potential biomarkers for diagnosis or treatment. These compounds …
diseases making them potential biomarkers for diagnosis or treatment. These compounds …
Revealing the molecular mechanisms of Alzheimer's disease based on network analysis
The complex pathology of Alzheimer's disease (AD) emphasises the need for
comprehensive modelling of the disease, which may lead to the development of efficient …
comprehensive modelling of the disease, which may lead to the development of efficient …
Computational Approaches to Assess Abnormal Metabolism in Alzheimer's Disease Using Transcriptomics
Transcriptome-integrated human genome-scale metabolic models (GEMs) have been used
widely to assess alterations in metabolism in response to disease. Transcriptome integration …
widely to assess alterations in metabolism in response to disease. Transcriptome integration …
[PDF][PDF] Systems Medicine for the Molecular Characterization of Alzheimer's Disease and the Drug Repurposing Strategy
Alzheimer's disease (AD) is a complex multifactorial brain disorder characterised by
dementia, neurodegeneration, plaques and neurofibrillary tangles in elderly people. The …
dementia, neurodegeneration, plaques and neurofibrillary tangles in elderly people. The …