The mechanical behavior of living cells is studied with micropipette suction in which the
surface of a cell is aspirated into a small glass tube while tracking the leading edge of its …

Biomechanical studies are expanding across a variety of fields, from biomedicine to
biomedical engineering. From the molecular to the system level, mechanical stimuli are …

Environmental factors are the largest contributors to cardiovascular disease. Here we show
that cardiac organoids that incorporate an oxygen-diffusion gradient and that are stimulated …

Microenvironments appear important in stem cell lineage specification but can be difficult to
adequately characterize or control with soft tissues. Naive mesenchymal stem cells (MSCs) …

Spatial patterns of cellular growth generate mechanical stresses that help to push, fold,
expand, and deform tissues into their specific forms. Genetic factors are thought to specify …

As physical entities, living cells possess structural and physical properties that enable them
to withstand the physiological environment as well as mechanical stimuli occurring within …

Mechanical factors play an important role in the regulation of cell physiology. One pathway
by which mechanical stress may influence gene expression is through a direct physical …

The tensegrity hypothesis holds that the cytoskeleton is a structure whose shape is
stabilized predominantly by the tensile stresses borne by filamentous structures …

This study evaluated the hypothesis that, due to functional and structural differences, the
apparent elastic modulus and viscous behavior of cardiac and skeletal muscle and vascular …

The interplay between the mechanical properties of cells and the forces that they produce
internally or that are externally applied to them play an important role in maintaining the …