Mesothelioma: Scientific clues for prevention, diagnosis, and therapy

M Carbone, PS Adusumilli… - CA: a cancer journal …, 2019‏ - Wiley Online Library
Mesothelioma affects mostly older individuals who have been occupationally exposed to
asbestos. The global mesothelioma incidence and mortality rates are unknown, because …

Perspectives on the treatment of malignant pleural mesothelioma

SM Janes, D Alrifai, DA Fennell - New England Journal of …, 2021‏ - Mass Medical Soc
Mesothelioma Most mesotheliomas originate in the pleura and are due to asbestos
exposure. The incidence is decreasing somewhat with asbestos remediation, but mortality …

Malignant pleural mesothelioma: ESMO Clinical Practice Guidelines for diagnosis, treatment and follow-up☆

S Popat, P Baas, C Faivre-Finn, N Girard… - Annals of …, 2022‏ - annalsofoncology.org
Incidence of malignant pleural mesothelioma (MPM) is generally higher in males than
females and is attributed to historical differences in exposures with world-standardised …

Extended pleurectomy decortication and chemotherapy versus chemotherapy alone for pleural mesothelioma (MARS 2): a phase 3 randomised controlled trial

E Lim, D Waller, K Lau, J Steele, A Pope… - The Lancet …, 2024‏ - thelancet.com
Background Extended pleurectomy decortication for complete macroscopic resection for
pleural mesothelioma has never been evaluated in a randomised trial. The aim of this study …

[HTML][HTML] ERS/ESTS/EACTS/ESTRO guidelines for the management of malignant pleural mesothelioma

A Scherpereel, I Opitz, T Berghmans… - European …, 2020‏ - publications.ersnet.org
The European Respiratory Society (ERS)/European Society of Thoracic Surgeons
(ESTS)/European Association for Cardio-Thoracic Surgery (EACTS)/European Society for …

Bevacizumab for newly diagnosed pleural mesothelioma in the Mesothelioma Avastin Cisplatin Pemetrexed Study (MAPS): a randomised, controlled, open-label …

G Zalcman, J Mazieres, J Margery, L Greillier… - The Lancet, 2016‏ - thelancet.com
Background Malignant pleural mesothelioma is an aggressive cancer with poor prognosis,
linked to occupational asbestos exposure. Vascular endothelial growth factor is a key …

Treatment of malignant pleural mesothelioma: American Society of Clinical Oncology clinical practice guideline

HL Kindler, N Ismaila, SG Armato III… - Journal of Clinical …, 2018‏ - ascopubs.org
Purpose To provide evidence-based recommendations to practicing physicians and others
on the management of malignant pleural mesothelioma. Methods ASCO convened an …

Novel insights into mesothelioma biology and implications for therapy

TA Yap, JG Aerts, S Popat, DA Fennell - Nature Reviews Cancer, 2017‏ - nature.com
Malignant mesothelioma is a universally lethal cancer that is increasing in incidence
worldwide. There is a dearth of effective therapies, with only one treatment (pemetrexed and …

Malignant pleural mesothelioma: an update on investigation, diagnosis and treatment

AC Bibby, S Tsim, N Kanellakis, H Ball… - European …, 2016‏ - publications.ersnet.org
Malignant pleural mesothelioma is an aggressive malignancy of the pleural surface,
predominantly caused by prior asbestos exposure. There is a global epidemic of malignant …

Pulmonary metastasectomy versus continued active monitoring in colorectal cancer (PulMiCC): a multicentre randomised clinical trial

T Treasure, V Farewell, F Macbeth, K Monson… - Trials, 2019‏ - Springer
Background Lung metastasectomy in the treatment of advanced colorectal cancer has been
widely adopted without good evidence of survival or palliative benefit. We aimed to test its …