The present advances in biology are related to progress in genomics, proteomics, and other
“-omics”, including glycomics, working with a large amount of data regarding human and …

A variety of neurodegenerative diseases are associated with amyloid plaques, which begin
as soluble protein oligomers but develop into amyloid fibrils. Our incomplete understanding …

Therapeutic proteins such as antibodies constitute the most rapidly growing class of
pharmaceuticals for use in diverse clinical settings including cancer, chronic inflammatory …

Mechanistic understanding of nucleation dependent polymerization by α-synuclein (α-Syn)
into toxic oligomers and amyloids is important for the drug development against Parkinson's …

The role of peptides Aβ40 and Aβ42 in the early pathogenesis of Alzheimer's disease (AD)
is frequently emphasized in the literature. It is known that Aβ42 is more prone to aggregation …

In order to clarify the mechanism of denaturant-induced unfolding of proteins we have
calculated the interactions between hydrophobic and ionic species in aqueous guanidinium …

The progress toward understanding the molecular basis of Alzheimers's disease is strongly
connected to elucidating the early aggregation events of the amyloid-β (Aβ) peptide …

In amyloid aggregation diseases soluble proteins coalesce into a wide array of undesirable
structures, ranging through oligomers and prefibrillar assemblies to highly ordered amyloid …

Amyloid fibrils are self‐assembled fibrous protein aggregates that are associated with a
number of presently incurable diseases such as Alzheimer's and Parkinson's disease …

Beta-amyloid (Aβ) aggregation has been strongly associated with the neurodegenerative
pathology and a cascade of harmful event rated to Alzheimer's disease (AD). Inhibition of Aβ …