Preterm fetuses and newborns have a high risk of neural injury and impaired neural
maturation, leading to neurodevelopmental disability. Develo** effective treatments is …

Most studies on single ventricle (SV) circulation take a physiological or anatomical
approach. Although there is a tight coupling between cardiac contractility and metabolism …

Babies born with fetal growth restriction (FGR) are at higher risk of develo**
cardiometabolic diseases across the life course. The reduction in substrate supply to the …

Mammalian cardiomyocytes become terminally-differentiated during the perinatal period. In
rodents, cytokinesis ceases after a final division cycle immediately after birth. Nuclear …

Brief repeated fetal hypoxaemia during labour can trigger intrapartum decelerations of the
fetal heart rate (FHR) via the peripheral chemoreflex or the direct effects of myocardial …

Fetal growth restriction (FGR) increases the risk cardiovascular disease (CVD) in adulthood.
Placental insufficiency and subsequent chronic fetal hypoxemia are causal factors for FGR …

At birth, the fetus experiences a dramatic change in environment that is accompanied by a
shift in myocardial fuel preference from lactate and glucose in fetal life to fatty acid oxidation …

Introduction: Adult patients with atrial septal defects (ASD), the most common form of adult
congenital heart disease, often die of arrhythmias, and the immaturity of cardiomyocytes …

It is not uncommon for a patient to experience hemodynamic instability following birth. This is
due to the fact that the transitional period requires dramatic cardiorespiratory changes …

The adult mammalian heart is unable to undergo cardiac repair, limiting potential treatment
options after cardiac damage. However, the fetal heart is capable of cardiac repair. In …