Despite the increasing use and success of interventional coronary reperfusion strategies,
morbidity and mortality from acute myocardial infarction are still substantial. Myocardial …

Reperfusion is mandatory to salvage ischemic myocardium from infarction, but reperfusion
per se contributes to injury and ultimate infarct size. Therefore, cardioprotection beyond that …

Kynurenic acid (KynA) is tissue protective in cardiac, cerebral, renal, and retinal ischemia
models, but the mechanism is unknown. KynA can bind to multiple receptors, including the …

Intermittent hypoxia (IH) has been the subject of considerable research in recent years, and
triggers a bewildering array of both detrimental and beneficial effects in multiple …

Myocardial infarct size is a major determinant of prognosis. Ischaemic preconditioning with
brief coronary occlusion and reperfusion before a sustained period of coronary occlusion …

How is the heartbeat generated? What controls the strength of contraction of heart muscle?
What are the links between cardiac structure and function? How does our understanding of …

This article updates the 1994 American Heart Association scientific statement on cardiac
rehabilitation. It provides a review of recommended components for an effective cardiac …

Heart diseases due to myocardial ischemia, such as myocardial infarction or ischemic heart
failure, are major causes of death in developed countries, and their number is unfortunately …

Yellon, Derek M., and James M. Downey. Preconditioning the Myocardium: From Cellular
Physiology to Clinical Cardiology. Physiol Rev 83: 1113-1151, 2003; 10.1152/physrev …

Remote ischaemic conditioning (RIC) triggers endogenous protective pathways in distant
organs such as the kidney, heart and brain, and represents an exciting new paradigm in …