Protein cages: from fundamentals to advanced applications
Proteins that self-assemble into polyhedral shell-like structures are useful molecular
containers both in nature and in the laboratory. Here we review efforts to repurpose diverse …
containers both in nature and in the laboratory. Here we review efforts to repurpose diverse …
[HTML][HTML] Structure and function of legumain in health and disease
The last years have seen a steady increase in our understanding of legumain biology that is
driven from two largely uncoupled research arenas, the mammalian and the plant legumain …
driven from two largely uncoupled research arenas, the mammalian and the plant legumain …
Functional genome analysis of Bifidobacterium breve UCC2003 reveals type IVb tight adherence (Tad) pili as an essential and conserved host-colonization factor
Development of the human gut microbiota commences at birth, with bifidobacteria being
among the first colonizers of the sterile newborn gastrointestinal tract. To date, the genetic …
among the first colonizers of the sterile newborn gastrointestinal tract. To date, the genetic …
Sortase enzymes in Gram‐positive bacteria
T Spirig, EM Weiner, RT Clubb - Molecular microbiology, 2011 - Wiley Online Library
In Gram‐positive bacteria proteins are displayed on the cell surface using sortase enzymes.
These cysteine transpeptidases join proteins bearing an appropriate sorting signal to …
These cysteine transpeptidases join proteins bearing an appropriate sorting signal to …
Evaluation of the Function of Probiotics, Emphasizing the Role of their Binding to the Intestinal Epithelium in the Stability and their Effects on the Immune System
N Javanshir, GNG Hosseini, M Sadeghi… - Biological procedures …, 2021 - Springer
Due to the importance of using cost-effective methods for therapeutic purposes, the function
of probiotics as safe microorganisms and the study of their relevant functional mechanisms …
of probiotics as safe microorganisms and the study of their relevant functional mechanisms …
Drug and vaccine development for the treatment and prevention of urinary tract infections
VP O'brien, TJ Hannan, HV Nielsen… - Urinary Tract Infections …, 2017 - Wiley Online Library
Urinary tract infections (UTI) are one of the most common bacterial infections, with roughly
eleven‐million cases reported in the US each year that cost an estimated $5 billion annually …
eleven‐million cases reported in the US each year that cost an estimated $5 billion annually …
Development of new spiro [1, 3] dithiine-4, 11′-indeno [1, 2-b] quinoxaline derivatives as S. aureus Sortase A inhibitors and radiosterilization with molecular …
Multi-drug resistant microbes have become a severe threat to human health and arise a
worldwide concern. A total of fifteen spiro-1, 3-dithiinoindenoquinoxaline derivatives 2–7 …
worldwide concern. A total of fifteen spiro-1, 3-dithiinoindenoquinoxaline derivatives 2–7 …
Architects at the bacterial surface—sortases and the assembly of pili with isopeptide bonds
APA Hendrickx, JM Budzik, SY Oh… - Nature Reviews …, 2011 - nature.com
The cell wall envelope of Gram-positive bacteria can be thought of as a surface organelle for
the assembly of macromolecular structures that enable the unique lifestyle of each …
the assembly of macromolecular structures that enable the unique lifestyle of each …
Molecular insights into probiotic mechanisms of action employed against intestinal pathogenic bacteria
Gastrointestinal (GI) diseases, and in particular those caused by bacterial infections, are a
major cause of morbidity and mortality worldwide. Treatment is becoming increasingly …
major cause of morbidity and mortality worldwide. Treatment is becoming increasingly …
Research progress in enzymatically cross-linked hydrogels as injectable systems for bioprinting and tissue engineering
Hydrogels have been developed for different biomedical applications such as in vitro culture
platforms, drug delivery, bioprinting and tissue engineering. Enzymatic cross-linking has …
platforms, drug delivery, bioprinting and tissue engineering. Enzymatic cross-linking has …