Obesity-induced neuroinflammation: beyond the hypothalamus

O Guillemot-Legris, GG Muccioli - Trends in neurosciences, 2017 - cell.com
Obesity is now a worldwide health issue. Far from being limited to weight gain, obesity is
generally associated with low-grade inflammation and with a cluster of disorders collectively …

Recent Advances in Momordica charantia: Functional Components and Biological Activities

S Jia, M Shen, F Zhang, J **e - International journal of molecular sciences, 2017 - mdpi.com
Momordica charantia L.(M. charantia), a member of the Cucurbitaceae family, is widely
distributed in tropical and subtropical regions of the world. It has been used in folk medicine …

The obese brain: mechanisms of systemic and local inflammation, and interventions to reverse the cognitive deficit

V Salas-Venegas, RP Flores-Torres… - Frontiers in Integrative …, 2022 - frontiersin.org
Overweight and obesity are now considered a worldwide pandemic and a growing public
health problem with severe economic and social consequences. Adipose tissue is an organ …

Obesity-induced blood-brain barrier dysfunction: phenotypes and mechanisms

Z Feng, C Fang, Y Ma, J Chang - Journal of Neuroinflammation, 2024 - Springer
Obesity, a burgeoning global health issue, is increasingly recognized for its detrimental
effects on the central nervous system, particularly concerning the integrity of the blood-brain …

Metabolic inflammation—a role for hepatic inflammatory pathways as drivers of comorbidities in nonalcoholic fatty liver disease?

N Gehrke, JM Schattenberg - Gastroenterology, 2020 - Elsevier
Nonalcoholic fatty liver disease (NAFLD) is a global and growing health concern. Emerging
evidence points toward metabolic inflammation as a key process in the fatty liver that …

Momordica charantia, a Nutraceutical Approach for Inflammatory Related Diseases

M Bortolotti, D Mercatelli, L Polito - Frontiers in pharmacology, 2019 - frontiersin.org
Momordica charantia, commonly called bitter melon, is a plant belonging to Cucurbitaceae
family known for centuries for its pharmacological activities, and nutritional properties. Due …

[HTML][HTML] Neuroinflammation and neurodegeneration in overnutrition-induced diseases

D Cai - Trends in Endocrinology & Metabolism, 2013 - cell.com
Overnutrition-induced diseases such as obesity and type 2 diabetes (T2D) involve neural
dysregulation of metabolic physiology. Recently, interdisciplinary research in neuroscience …

Fatty acids: an insight into the pathogenesis of neurodegenerative diseases and therapeutic potential

DJ Vesga-Jiménez, C Martin, GE Barreto… - International journal of …, 2022 - mdpi.com
One of the most common lipids in the human body is palmitic acid (PA), a saturated fatty acid
with essential functions in brain cells. PA is used by cells as an energy source, besides …

Bitter melon: a panacea for inflammation and cancer

PR Dandawate, D Subramaniam, SB Padhye… - Chinese journal of …, 2016 - Elsevier
Nature is a rich source of medicinal plants and their products that are useful for treatment of
various diseases and disorders. Momordica charantia, commonly known as bitter melon or …

The entrancing role of dietary polyphenols against the most frequent aging‐associated diseases

MA Shah, HI Faheem, A Hamid… - Medicinal Research …, 2024 - Wiley Online Library
Aging, a fundamental physiological process influenced by innumerable biological and
genetic pathways, is an important driving factor for several aging‐associated disorders like …