A wide variety of laboratory apparatuses have been devised for mechanical stimulation of
cell and tissue cultures. This article reviews the functional attributes of several dozen …

This review describes research on selected peptide sequences that affect cell adhesion as it
applies in orthopedic applications. Of particular interest are the integrin-binding RGD …

This second edition of the Bone Mechanics Handbook summarizes the current
understanding of bone mechanics with comprehensive coverage of the histology …

An interdisciplinary study based on animal experiments, cell culture studies, and finite
element models is presented. In a sheep model, the influence of the osteotomy gap size and …

Although it is well accepted that bone tissue metabolism is regulated by external mechanical
loads, it remains unclear to what load-induced physical signals bone cells respond. In this …

Recently fluid flow has been shown to be a potent physical stimulus in the regulation of bone
cell metabolism. However, most investigators have applied steady or pulsing flow profiles …

It has been observed that the polished neck of dental implants does not osseointegrate as
do textured surfaces. Similar findings were reported in the orthopedic literature on artificial …

Bone is a dynamic tissue that is able to sense and adapt to mechanical stimuli by
modulating its mass, geometry, and structure. Bone marrow stromal cells (BMSCs) are …

This study tested the effects of hydrostatic pressure (10 MPa) on adult articular chondrocyte
mRNA and extracellular matrix synthesis in vitro. High density primary cultures of bovine …

The effects of mechanical stability and mechanical stimulation have been studied
extensively in vivo using a variety of animal models and stimulators. Early results indicated …