Modulation of host immunity by helminths: the expanding repertoire of parasite effector molecules
Helminths are extraordinarily successful parasites due to their ability to modulate the host
immune response. They have evolved a spectrum of immunomodulatory molecules that are …
immune response. They have evolved a spectrum of immunomodulatory molecules that are …
Innate immune receptors in platelets and platelet-leukocyte interactions
PRB Dib, AC Quirino-Teixeira, LB Merij… - Journal of Leucocyte …, 2020 - academic.oup.com
Platelets are chief cells in hemostasis. Apart from their hemostatic roles, platelets are major
inflammatory effector cells that can influence both innate and adaptive immune responses …
inflammatory effector cells that can influence both innate and adaptive immune responses …
Schistosome egg migration: mechanisms, pathogenesis and host immune responses
Many parasitic worms possess complex and intriguing life cycles, and schistosomes are no
exception. To exit the human body and progress to their successive snail host, Schistosoma …
exception. To exit the human body and progress to their successive snail host, Schistosoma …
Patrolling the vascular borders: platelets in immunity to infection and cancer
Platelets are small anucleate cellular fragments that are released by megakaryocytes and
safeguard vascular integrity through a process termed 'haemostasis'. However, platelets …
safeguard vascular integrity through a process termed 'haemostasis'. However, platelets …
Vesicle-based secretion in schistosomes: Analysis of protein and microRNA (miRNA) content of exosome-like vesicles derived from Schistosoma mansoni
Exosomes are small vesicles of endocytic origin, which are released into the extracellular
environment and mediate a variety of physiological and pathological conditions. Here we …
environment and mediate a variety of physiological and pathological conditions. Here we …
Schistosoma mansoni Egg, Adult Male and Female Comparative Gene Expression Analysis and Identification of Novel Genes by RNA-Seq
Background Schistosomiasis is one of the most prevalent parasitic diseases worldwide and
is a public health problem. Schistosoma mansoni is the most widespread species …
is a public health problem. Schistosoma mansoni is the most widespread species …
Schistosoma mansoni SmKI-1 serine protease inhibitor binds to elastase and impairs neutrophil function and inflammation
SB Morais, BC Figueiredo, NRG Assis… - PLoS …, 2018 - journals.plos.org
Protease inhibitors have important function during homeostasis, inflammation and tissue
injury. In this study, we described the role of Schistosoma mansoni Sm KI-1 serine protease …
injury. In this study, we described the role of Schistosoma mansoni Sm KI-1 serine protease …
Eosinophils and macrophages within the Th2-induced granuloma: balancing killing and healing in a tight space
Granuloma formation is a key host immune response generated to confine invading
pathogens and limit extensive host damage. It consists of an accumulation of host immune …
pathogens and limit extensive host damage. It consists of an accumulation of host immune …
The human blood parasite Schistosoma mansoni expresses extracellular tegumental calpains that cleave the blood clotting protein fibronectin
Schistosomes are intravascular, parasitic flatworms that cause debilitating disease afflicting>
200 million people. Proteins expressed at the host-parasite interface likely play key roles in …
200 million people. Proteins expressed at the host-parasite interface likely play key roles in …
Moonlighting proteins as virulence factors of pathogenic fungi, parasitic protozoa and multicellular parasites
J Karkowska‐Kuleta, A Kozik - Molecular Oral Microbiology, 2014 - Wiley Online Library
The delicate balance between eukaryotic pathogens and their human hosts during the
initiation and development of infection is a complex process involving many diverse …
initiation and development of infection is a complex process involving many diverse …