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Next-generation lineage tracing and fate map** to interrogate development
Lineage tracing and fate map**, overlap** yet distinct disciplines to follow cells and
their progeny, have evolved rapidly over the last century. Lineage tracing aims to identify all …
their progeny, have evolved rapidly over the last century. Lineage tracing aims to identify all …
Cellular dynamics of EMT: lessons from live in vivo imaging of embryonic development
Epithelial-mesenchymal transition (EMT) refers to a process in which epithelial cells lose
apical-basal polarity and loosen cell–cell junctions to take on mesenchymal cell …
apical-basal polarity and loosen cell–cell junctions to take on mesenchymal cell …
Iterative tomography with digital adaptive optics permits hour-long intravital observation of 3D subcellular dynamics at millisecond scale
Long-term subcellular intravital imaging in mammals is vital to study diverse intercellular
behaviors and organelle functions during native physiological processes. However, optical …
behaviors and organelle functions during native physiological processes. However, optical …
Long-term intravital subcellular imaging with confocal scanning light-field microscopy
Wide field light-sheet microscopy with lens-axicon controlled two-photon Bessel beam illumination
Two-photon excitation can lower phototoxicity and improve penetration depth, but its narrow
excitation range restricts its applications in light-sheet microscopy. Here, we propose simple …
excitation range restricts its applications in light-sheet microscopy. Here, we propose simple …
Intravital imaging of mouse embryos
Embryonic development is a complex process that is unamenable to direct observation. In
this study, we implanted a window to the mouse uterus to visualize the develo** embryo …
this study, we implanted a window to the mouse uterus to visualize the develo** embryo …
Efficient processing and analysis of large-scale light-sheet microscopy data
Light-sheet microscopy is a powerful method for imaging the development and function of
complex biological systems at high spatiotemporal resolution and over long time scales …
complex biological systems at high spatiotemporal resolution and over long time scales …