Obesity, increasing in prevalence globally, is the clinical condition most strongly associated
with lowered testosterone concentrations in men and presents as one of the strongest …

Abstract Purpose of Review The purpose of this review is to analyze the link between
testosterone replacement therapy (TRT) and adverse cardiovascular (CV) events. Recent …

In male mammals, changes at all levels of the hypothalamic-pituitary-testicular axis,
including alterations in the GnRH pulse generator, gonadotropin secretion, and testicular …

Purpose: An unsafe hematocrit threshold for men receiving testosterone therapy (TT) has
never been tested. This study seeks to determine whether secondary polycythemia among …

Cardiovascular disease (CVD) is the leading cause of death in the US and worldwide. Sex-
related disparities have been identified in the presentation and incidence rate of CVD …

The pursuit of longevity, which during the Renaissance era was limited to longing for
miraculous ways of rejuvenation, such as bathing in the fountain of youth, took a scientific …

Testosterone is often used to improve the physiological function. But increased testosterone
levels affect blood lipids and cause inflammation and oxidative stress, which are risk factors …

The increasing rate of late-onset hypogonadism has led to an exceptional growth in the use
of testosterone therapy (TTh). Even though TTh has been used for more than 70 years, there …

In this issue of Asian Journal of Andrology (AJA), several experts have reviewed the latest
data on the potential and known effects of endogenous and exogenous testosterone (T) on …

Epidemiological studies hint at a beneficial influence of endogenous circulating testosterone
(T), or its metabolite dihydrotestosterone (DHT), such that men with lower concentrations of T …