Cancer is the second leading cause of mortality globally which remains a continuing threat
to human health today. Drug insensitivity and resistance are critical hurdles in cancer …

The present review article offers a detailed account of the design strategies employed for the
synthesis of nitrogen-containing anticancer agents. The results of different studies describe …

The topoisomerase enzymes play an important role in DNA metabolism, and searching for
enzyme inhibitors is an important target in the search for new anticancer drugs. Discovery of …

This review summarized the current breakthroughs in the chemistry of acridines as anti-
cancer agents, including new structural and biologically active acridine attributes. Acridine …

Benzimidazole, a fused heterocycle bearing benzene and imidazole has gained
considerable attention in the field of contemporary medicinal chemistry. The moiety is of …

Many people in the world struggle with cancer or bacterial, parasitic, viral, Alzheimer's and
other diseases. Therefore, many scientists seek new, more effective, more selective and less …

Cancer is one of the leading causes of death worldwide. Mutation of the cell regulates genes
and protein causing cancer. Surgery, radiotherapy, and the use of anticancer agents are the …

Cancer, also known as malignant neoplasm, is a dreadful disease which involves abnormal
cell growth having the potential to invade or spread to other parts of the body …

Cancer is one of the most serious medical problem and second leading cause of death in
the world, characterized by a deregulation of the cell cycle which mainly results in a …

TOPOI inhibitors have long been a focal point in the research and development of antitumor
drugs. PARP-1 plays a crucial role in repairing DNA damage induced by TOPOI inhibitors …