Surface chemistry of gold nanoparticles for health-related applications

J Zhang, L Mou, X Jiang - Chemical Science, 2020 - pubs.rsc.org
Functionalization of gold nanoparticles is crucial for the effective utilization of these materials
in health-related applications. Health-related applications of gold nanoparticles rely on the …

Stereospecific interactions between chiral inorganic nanomaterials and biological systems

X Zhao, SQ Zang, X Chen - Chemical Society Reviews, 2020 - pubs.rsc.org
Chirality is ubiquitous in nature and plays mysterious and essential roles in maintaining key
biological and physiological processes. As biological systems display high selectivity for …

C3N nanodots inhibits Aβ peptides aggregation pathogenic path in Alzheimer's disease

X Yin, H Zhou, M Zhang, J Su, X Wang, S Li… - Nature …, 2023 - nature.com
Despite the accumulating evidence linking the development of Alzheimer's disease (AD) to
the aggregation of Aβ peptides and the emergence of Aβ oligomers, the FDA has approved …

[HTML][HTML] Computer-aided nanodrug discovery: recent progress and future prospects

JJ Zheng, QZ Li, Z Wang, X Wang, Y Zhao… - Chemical Society …, 2024 - pubs.rsc.org
Nanodrugs, which utilise nanomaterials in disease prevention and therapy, have attracted
considerable interest since their initial conceptualisation in the 1990s. Substantial efforts …

Peptide‐based molecular strategies to interfere with protein misfolding, aggregation, and cell degeneration

V Armiento, A Spanopoulou… - Angewandte Chemie …, 2020 - Wiley Online Library
Protein misfolding into amyloid fibrils is linked to more than 40 as yet incurable cell‐and
neurodegenerative diseases such as Alzheimer's disease, Parkinson's disease, and type 2 …

Mitigation of amyloidosis with nanomaterials

PC Ke, EH Pilkington, Y Sun, I Javed… - Advanced …, 2020 - Wiley Online Library
Amyloidosis is a biophysical phenomenon of protein aggregation with biological and
pathogenic implications. Among the various strategies developed to date, nanomaterials …

A nanomedicine structure–activity framework for research, development, and regulation of future cancer therapies

B Youden, R Jiang, AJ Carrier, MR Servos, X Zhang - ACS nano, 2022 - ACS Publications
Despite their clinical success in drug delivery applications, the potential of theranostic
nanomedicines is hampered by mechanistic uncertainty and a lack of science-informed …

[HTML][HTML] The roles of gold nanoparticles in the detection of amyloid-β peptide for Alzheimer's disease

J Zhao, N Xu, X Yang, G Ling, P Zhang - Colloid and Interface Science …, 2022 - Elsevier
As the most common form of dementia in humans, Alzheimer's disease (AD) is linked to
misfolding and aggregation of amyloid-β (Aβ) peptides. Gold nanoparticles (AuNPs) can …

[HTML][HTML] The role of surfaces on amyloid formation

F Grigolato, P Arosio - Biophysical Chemistry, 2021 - Elsevier
Interfaces can strongly accelerate or inhibit protein aggregation, destabilizing proteins that
are stable in solution or, conversely, stabilizing proteins that are aggregation-prone …

Conversion of waste eggshell into difunctional Au/CaCO3 nanocomposite for 4-Nitrophenol electrochemical detection and catalytic reduction

Q Ding, Z Kang, L Cao, M Lin, H Lin, DP Yang - Applied Surface Science, 2020 - Elsevier
Eggshell is renewable, abundantly available and economic. It holds great business
potentials if eggshell as waste can be converted into valuable functional materials for …