Tissue imaging has become much more colourful in the past decade. Advances in both
experimental and analytical methods now make it possible to image protein markers in …

Many solid tumors exhibit significant genetic, cellular, and biophysical heterogeneity which
dynamically evolves during disease progression and after treatment. This constant flux in …

Low‐grade serous ovarian carcinoma (LGSC) is a rare and lethal subtype of ovarian cancer.
LGSC is pathologically, biologically, and clinically distinct from the more common high …

Macrophages are involved in several critical activities associated with tissue repair and
regeneration. Current approaches in regenerative medicine are focusing on leveraging the …

Tissue-resident macrophages (TRMs) are an integral part of the innate immune system, but
their biology is not well understood in the context of cancer. Distinctive resident macrophage …

Reproduction consists of sequential inflammation-like events, primarily within the
endometrium, from ovulation to embryo implantation, decidualization and delivery. During …

Intercellular communication is fundamental to multicellular life and a core determinant of
outcomes during viral infection, where the common goals of virus and host for persistence …

Analyzing the local microenvironment of tumor cells can provide significant insights into their
complex interactions with their cellular surroundings, including immune cells. By quantifying …

Spatially resolved transcriptomics (SRT) techniques have revolutionized the characterization
of molecular profiles while preserving spatial and morphological context. However, most …

Ductal carcinoma in situ (DCIS) accounts for~ 20% of all breast cancer diagnoses but whilst
known to be a precursor of invasive breast cancer (IBC), evidence suggests only one in six …